Results 31 to 40 of about 18,304 (208)

Self-Organization of Blood Pressure Regulation: Experimental Evidence

Frontiers in Physiology, 2016
Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one.
Jacques-Olivier eFortrat, Thibaud eLevrard, sandrine ecourcinous, jacques evictor   +3 more
doaj   +1 more source

Effect of Head-Up/-Down Tilt on ECG Segments and Myocardial Temporal Dispersion in Healthy Subjects

Biology, 2023
The head-up/-down tilt test acutely modifies the autonomic nervous system balance throughout a deactivation of the cardiopulmonary reflexes. The present study examines the influence of head-up/-down tilt on a number of ECG segments. A total of 20 healthy
Gianfranco Piccirillo, Federica Moscucci, Ilaria Di Diego, Martina Mezzadri, Cristina Caltabiano, Myriam Carnovale, Andrea Corrao, Ilaria Lospinuso, Sara Stefano, Claudia Scinicariello, Marco Giuffrè, Valerio De Santis, Susanna Sciomer, Pietro Rossi, Emiliano Fiori, Damiano Magrì   +15 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Impact of Daily Lower‐Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest‐Induced Orthostatic Intolerance

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Orthostatic intolerance occurs following immobilization in patients on Earth and in astronauts after spaceflight. Head‐down tilt bedrest is a terrestrial model for weightlessness and induces orthostatic intolerance.
Jan‐Niklas Hönemann, Fabian Hoffmann, Laura de Boni, Peter Gauger, Edwin Mulder, Stefan Möstl, Karsten Heusser, Marie‐Therese Schmitz, Marcel Halbach, Steven S. Laurie, Stuart M. C. Lee, Brandon R. Macias, Jens Jordan, Jens Tank   +13 more
doaj   +1 more source

Cardiopulmonary Responses to Sub-Maximal Ergometer Exercise in a Hypo-Gravity Analog Using Head-Down Tilt and Head-Up Tilt

Frontiers in Physiology, 2019
After more than 50 years of spaceflight, we still do not know what is the appropriate range of gravity levels that are required to maintain normal physiological function in humans. This research effort aimed to investigate musculoskeletal, cardiovascular,
Ana Diaz-Artiles, Patricia Navarro Tichell, Francisca Perez   +2 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

P166 HEAD-DOWN TILT BED-REST SIGNIFICANTLY INCREASES CENTRAL ARTERIAL STIFFNESS

Artery Research, 2017
The vascular system is subject to continual variation in mechanical stresses, both physiological and pathological. Vascular remodeling via changes in vessel wall properties, including thickness and stiffness, is a major feature of aging and ...
Fouassier David, Hakim Khettab, Pierre Boutouyrie, Carole Leguy, Catalin Cristian   +4 more
doaj   +1 more source

The effect of pneumoperitoneum and Trendelenburg position on respiratory mechanics during pelviscopic surgery [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundConventional pelviscopic surgery requires pneumoperitoneum with CO2 gas insufflation and lithotomy-Trendelenburg position. Pneumoperitoneum and Trendelenburg position may influence intraoperative respiratory mechanics in anesthetic management ...
Min Kyo Suh, Kyu Wan Seong, Sung Hwan Jung, Seong Su Kim   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Effects of Head-down Tilt on Nerve Conduction in Rhesus Monkeys

Chinese Medical Journal, 2017
Background: Few studies have focused on peripheral nerve conduction during exposure to microgravity. The −6° head-down tilt (HDT) comprises an experimental model used to simulate the space flight environment.
Bo Sun, Xiao-Yun Zhang, Li-Zhi Liu, Zhao-Hui Chen, Zhong-Quan Dai, Xu-Sheng Huang   +5 more
doaj   +1 more source