Results 71 to 80 of about 360,174 (367)

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang   +6 more
wiley   +1 more source

Game on: immersive virtual laboratory simulation improves student learning outcomes & motivation

open access: yesFEBS Open Bio, 2023
The use of gamified learning interventions is expanding in postsecondary education as a means to improve students' motivation and learning outcomes. Virtual laboratory simulations have been used in science education to supplement students' learning, as ...
Danielle Tsirulnikov   +4 more
doaj   +1 more source

A Fitts' law study of click and dwell interaction by gaze, head and mouse with a head-mounted display

open access: yesCOGAIN@ETRA, 2018
Gaze and head tracking, or pointing, in head-mounted displays enables new input modalities for point-select tasks. We conducted a Fitts' law experiment with 41 subjects comparing head pointing and gaze pointing using a 300 ms dwell (n = 22) or click (n =
J. P. Hansen   +3 more
semanticscholar   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1517-1531, May 2025.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Head-Mounted Projector for Manual Precision Tasks: Performance Assessment

open access: yesSensors, 2023
The growing interest in augmented reality applications has led to an in-depth look at the performance of head-mounted displays and their testing in numerous domains.
Virginia Mamone   +5 more
doaj   +1 more source

ARssist: augmented reality on a head-mounted display for the first assistant in robotic surgery

open access: yesHealthcare technology letters, 2018
In robot-assisted laparoscopic surgery, the first assistant (FA) is responsible for tasks such as robot docking, passing necessary materials, manipulating hand-held instruments, and helping with trocar planning and placement. The performance of the FA is
Long Qian, A. Deguet, P. Kazanzides
semanticscholar   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits   +7 more
wiley   +1 more source

AUGMENTED REALITY AND EDUCATION SCIENCES

open access: yesInternational Journal of Social and Educational Innovation, 2020
The present paper reviews the field of Augmented Reality, starting from the current research and publications of this specialization, starting from the premise that augmenting reality implies an extension of virtual reality.
Cristian Pamparău
doaj  

Latency Requirements for Head-Worn Display S/EVS Applications [PDF]

open access: yes, 2004
NASA s Aviation Safety Program, Synthetic Vision Systems Project is conducting research in advanced flight deck concepts, such as Synthetic/Enhanced Vision Systems (S/EVS), for commercial and business aircraft.
Bailey, Randall E.   +2 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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