Results 61 to 70 of about 864,766 (302)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Evaluating the Consistency Between Numerical Calculation and Acoustic Measurement of Head-Related Transfer Functions

IEEE Access
In the validation of numerically calculated Head-Related Transfer Functions (HRTFs), acoustic measurements are often considered the ground truth. This study indicates that discrepancies between numerical and measured HRTFs may result from various factors
Chang Sun, Kan Okubo
doaj   +1 more source

Acoustic and non-acoustic factors in modeling listener-specific performance of sagittal-plane sound localization

Frontiers in Psychology, 2014
The ability of sound-source localization in sagittal planes (along the top-down and front-back dimension) varies considerably across listeners. The directional acoustic spectral features, described by head-related transfer functions (HRTFs), also vary ...
Piotr eMajdak, Robert eBaumgartner, Bernhard eLaback   +2 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Sound Source Localisation in Digital Hearing Aids: A Review of Critical Factors

Archives of Acoustics
Sound source localisation is a fundamental ability for a listener’s functional interaction with the environment, yet it remains a significant challenge for hearing aid users.
Fermín SCALITI, Diego A. EVIN, Fabián C. TOMMASINI   +2 more
doaj   +1 more source

Effect of Individualized Head-Related Transfer Functions on Distance Perception in Virtual Reproduction for a Nearby Sound Source

Archives of Acoustics, 2019
The head-related transfer function (HRTF) is dependent on the position of the sound source (both direction and distance) and is also affected by individual anatomical parameters.
Guangzheng YU, Liliang WANG
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Spatial Upsampling of Head-Related Transfer Function Using Neural Network Conditioned on Source Position and Frequency

IEEE Open Journal of Signal Processing
A spatial upsampling method for the head-related transfer function (HRTF) using deep neural networks (DNNs), consisting of an autoencoder conditioned on the source position and frequency, is proposed.
Yuki Ito, Tomohiko Nakamura, Shoichi Koyama, Shuichi Sakamoto, Hiroshi Saruwatari   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Influence of head morphology and natural postures on sound localization cues in crocodilians [PDF]

Royal Society Open Science, 2019
As top predators, crocodilians have an acute sense of hearing that is useful for their social life and for probing their environment in hunting situations.
L. Papet, N. Grimault, N. Boyer, N. Mathevon   +3 more
doaj   +1 more source