Results 251 to 260 of about 1,600,059 (380)

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

The Limitations of Artificial Intelligence in Head and Neck Oncology. [PDF]

Adv Ther
Rao KN, Fernandez-Alvarez V, Guntinas-Lichius O, Sreeram MP, de Bree R, Kowalski LP, Forastiere A, Pace-Asciak P, Rodrigo JP, Saba NF, Ronen O, Florek E, Randolph GW, Sanabria A, Vermorken JB, Hanna EY, Ferlito A.   +16 more
europepmc   +1 more source

ORIGIN AND SIGNIFICANCE OF VASCULAR MURMURS OF THE HEAD AND NECK

, 1962
Norman Allen, VERNON MUSTIAN
openalex   +1 more source

Giant granulomatous lesions of the femoral head and neck in rheumatoid arthritis. [PDF]

, 1970
CL Colton, A. J. Darby
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Future Perspectives in Senescence-Based Therapies for Head and Neck Cancer. [PDF]

Cancers (Basel)
Palomares BH, Martins MD, Martins MAT, Squarize CH, Castilho RM.   +4 more
europepmc   +1 more source

BLEOMYCIN IN MALIGNANT TUMORS OF HEAD AND NECK

, 1969
Yasunobu Suzuki, Hirosato Miyake, Makoto Sakai, Yukio Inuyama, J Matsukawa, Kazuyoshi Fujii   +5 more
openalex   +2 more sources

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

The practice of oral feeding after total laryngectomy by Brazilian head and neck surgeons. [PDF]

Braz J Otorhinolaryngol
Benali J, Ayad T, Ceccon FP, Chiesa-Estomba C, Lechien JR, Aires MM, Haddad L, Viljoen G, Fakhry N.   +8 more
europepmc   +1 more source