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Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.
New England Journal of Medicine, 2006 BACKGROUND
We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor receptor, in the treatment of locoregionally advanced squamous-cell ...J. Bonner, P. Harari, J. Giralt, N. Azarnia, D. Shin, R. Cohen, Christopher U. Jones, R. Sur, D. Raben, J. Jassem, R. Ove, M. Kies, J. Baselga, H. Youssoufian, N. Amellal, E. Rowinsky, E. Rowinsky, K. Ang +17 moresemanticscholar +1 more sourceComprehensive genomic characterization of head and neck squamous cell carcinomas
Nature, 2015 The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations.M. Lawrence, C. Sougnez, Lee T Lichtenstein, K. Cibulskis, E. Lander, S. Gabriel, G. Getz, Adrian Ally, M. Balasundaram, I. Birol, R. Bowlby, Denise Brooks, Y. Butterfield, R. Carlsen, Dean Cheng, Andy Chu, Noreen Dhalla, R. Guin, R. Holt, Steven J. M. Jones, Darlene Lee, H. Li, M. Marra, Michael Mayo, Richard A. Moore, A. Mungall, A. G. Robertson, J. Schein, Payal Sipahimalani, Angela Tam, N. Thiessen, Tina Wong, A. Protopopov, Netty G Santoso, Semin Lee, Michael G Parfenov, Jianhua Zhang, Harshad S. Mahadeshwar, Jiabin Tang, X. Ren, S. Seth, Psalm S. Haseley, Dong Zeng, Lixing Yang, A. W. Xu, Xingzhi Song, A. Pantazi, C. Bristow, Angela Hadjipanayis, J. Seidman, L. Chin, P. Park, R. Kucherlapati, Rehan Akbani, Tod D. Casasent, Wenbin Liu, Yiling Lu, G. Mills, Thomas C. Motter, J. Weinstein, L. Diao, Jing Wang, Youhong Fan, Jinze Liu, Kai Wang, J. Auman, S. Balu, T. Bodenheimer, Elizabeth Buda, D. Hayes, K. Hoadley, A. Hoyle, S. Jefferys, Corbin D. Jones, P. Kimes, Yufeng Liu, J. Marron, S. Meng, P. Mieczkowski, Lisle E. Mose, J. Parker, C. Perou, J. Prins, J. Roach, Yan Shi, J. Simons, Darshan Singh, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, Vonn Walter, S. Waring, M. Wilkerson, Junyuan Wu, N. Zhao, A. Cherniack, P. Hammerman, A. Tward, C. Pedamallu, G. Saksena, Joonil Jung, A. Ojesina, S. Carter, Travis Zack, S. Schumacher, R. Beroukhim, S. Freeman, M. Meyerson, Juok Cho, M. Noble, D. Dicara, Hailei Zhang, David I Heiman, Nils Gehlenborg, Douglas Voet, Pei Lin, S. Frazer, P. Stojanov, Yingchun Liu, L. Zou, Jaegil Kim, D. Muzny, H. Doddapaneni, C. Kovar, J. Reid, Donna Morton, Yi Han, Walker Hale, H. Chao, K. Chang, J. Drummond, R. Gibbs, N. Kakkar, D. Wheeler, Liu Xi, G. Ciriello, M. Ladanyi, William Lee, Ricardo Ramirez, C. Sander, R. Shen, Rileen Sinha, Nils Weinhold, B. Taylor, B. A. Aksoy, Gideon Dresdner, Jianjiong Gao, Benjamin E. Gross, A. Jacobsen, B. Reva, N. Schultz, S. O. Sumer, Yichao Sun, T. Chan, L. Morris, Joshua M. Stuart, S. Benz, S. Ng, C. Benz, C. Yau, S. Baylin, L. Cope, Ludmila V. Danilova, J. Herman, Moiz Bootwalla, D. Maglinte, P. Laird, T. Triche, D. Weisenberger, D. V. Berg, N. Agrawal, J. Bishop, P. Boutros, J. Bruce, L. Byers, J. Califano, T. Carey, Zhong Chen, Hui Cheng, Simion I. Chiosea, E. Cohen, B. Diergaarde, A. Egloff, A. El-Naggar, R. Ferris, M. Frederick, J. Grandis, Yanzhu Guo, R. Haddad, Thomas M. Harris, A. Hui, J. Lee, S. Lippman, Fei-Fei Liu, J. Mchugh, J. Myers, P. Ng, B. Perez–Ordoñez, C. Pickering, M. Prystowsky, M. Romkes, Anthony D Saleh, M. Sartor, R. Seethala, T. Seiwert, H. Si, C. Waes, Daryl Waggott, M. Wiznerowicz, W. Yarbrough, Jiexin Zhang, Zhixiang Zuo, K. Burnett, D. Crain, J. Gardner, Kevin R Lau, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, M. Sherman, P. Yena, Aaron D. Black, Jay Bowen, J. Frick, J. Gastier-Foster, H. Harper, K. Leraas, T. Lichtenberg, N. Ramirez, L. Wise, E. Zmuda, J. Baboud, M. Jensen, A. Kahn, T. Pihl, D. Pot, Deepak Srinivasan, Jessica L Walton, Yunhu Wan, R. Burton, Tanja Davidsen, John A. Demchok, G. Eley, M. Ferguson, K. Shaw, B. Ozenberger, Margi Sheth, H. Sofia, R. Tarnuzzer, Zhining Wang, Liming Yang, J. Zenklusen, Charles Saller, Katherine Tarvin, Chu Chen, R. Bollag, P. Weinberger, W. Golusiński, P. Golusiński, Matthew Ibbs, Konstanty Korski, A. Mackiewicz, W. Suchorska, Bartosz Szybiak, Erin E. Curley, C. Beard, Colleen M. Mitchell, G. Sandusky, Julie Ahn, Zubair Khan, J. Irish, J. Waldron, W. William, Sophie C. Egea, C. Gomez-Fernandez, Lynn M. Herbert, C. Bradford, D. Chepeha, Andrea Haddad, Tamara R. Jones, Christine M. Komarck, Mayya Malakh, J. Moyer, Ariane Nguyen, Lisa A. Peterson, M. Prince, L. Rozek, Evan G. Taylor, H. Walline, G. Wolf, L. Boice, B. Chera, W. Funkhouser, M. Gulley, T. Hackman, M. Hayward, Meijuan Huang, W. Rathmell, Ashley H. Salazar, W. Shockley, C. Shores, L. Thorne, M. Weissler, Sylvia Wrenn, A. Zanation, Brandee T. Brown, M. Pham +309 moresemanticscholar +1 more sourceExploration of Predictive Biomarkers for Postoperative Recurrence in Chronic Rhinosinusitis with Nasal Polyps Based on Serum Multiple-Cytokine Profiling
Mediators of Inflammation, 2022 Background. Functional nasal endoscopic surgery (FESS) is an effective treatment approach for chronic rhinosinusitis with nasal polyps (CRSwNP) patients, but some patients still suffer from postoperative recurrence.Gang Wang, Huiyuan Zheng, Xiaoqian Chen, Jing Zheng, Jiabin Zhan, Rui Li, Yanyan Qi, Yi Ye, Min Zeng, Xin Wei +9 moredoaj +1 more sourceCirculating MMP-12 as Potential Biomarker in Evaluating Disease Severity and Efficacy of Sublingual Immunotherapy in Allergic Rhinitis
Mediators of Inflammation, 2022 Background. Allergic rhinitis (AR) is a highly heterogeneous disease, and allergen-specific immunotherapy (AIT) is an effective treatment. This study aims to evaluate the circulating mas-related G protein-coupled receptor-X2 (MRGPRX2) and matrix ...Yandan Zhou, Min Xu, Wei Gong, Xiaoming Kang, Renzhong Guo, Jie Wen, Dinggang Zhou, Manjing Wang, Dazhi Shi, Qiancheng Jing +9 moredoaj +1 more sourcePlatinum-based chemotherapy plus cetuximab in head and neck cancer.
New England Journal of Medicine, 2008 BACKGROUND
Cetuximab is effective in platinum-resistant recurrent or metastatic squamous-cell carcinoma of the head and neck. We investigated the efficacy of cetuximab plus platinum-based chemotherapy as first-line treatment in patients with recurrent or J. Vermorken, R. Mesía, F. Rivera, É. Remenár, A. Kawecki, S. Rottey, J. Erfán, D. Zabolotnyy, H. Kienzer, D. Cupissol, F. Peyrade, M. Benasso, I. Vynnychenko, D. de Raucourt, C. Bokemeyer, A. Schueler, N. Amellal, R. Hitt +17 moresemanticscholar +1 more source