Results 41 to 50 of about 742,331 (314)

Circulating MMP-12 as Potential Biomarker in Evaluating Disease Severity and Efficacy of Sublingual Immunotherapy in Allergic Rhinitis

Mediators of Inflammation, 2022
Background. Allergic rhinitis (AR) is a highly heterogeneous disease, and allergen-specific immunotherapy (AIT) is an effective treatment. This study aims to evaluate the circulating mas-related G protein-coupled receptor-X2 (MRGPRX2) and matrix ...
Yandan Zhou, Min Xu, Wei Gong, Xiaoming Kang, Renzhong Guo, Jie Wen, Dinggang Zhou, Manjing Wang, Dazhi Shi, Qiancheng Jing   +9 more
doaj   +1 more source

Desmoid tumors of the head and neck: A therapeutic challenge

, 2014
Item does not contain fulltextDesmoid tumor, or aggressive fibromatosis, is a rare, histologically benign, fibroblastic lesion that infrequently presents in the head and neck.
Eelco de Bree, Shaha, Ashok R., Zoras, O., Bree, R. de, Hunt, Jennifer L., Ferlito, Alfio, Remco de Bree, Takes, Robert P., Alessandra Rinaldo, Mendenhall, William M., Michael L. Hinni, Hunt, J.L., Rinaldo, Alessandra, Jennifer L. Hunt, Juan P. Rodrigo, Mendenhall, W.M., Rodrigo Tapia, Juan Pablo, Bree, Remco de, Takes, R.P., Ferlito, A., Suárez Nieto, Carlos, Hinni, Michael L., Alfio Ferlito, de Bree, E., Zoras, Odysseas, Robert P. Takes, Carlos Suárez, Odysseas Zoras, Bree, Eelco de, de Bree, R., Ashok R. Shaha, Suarez, C., Shaha, A.R., William M. Mendenhall, Bree, E. de, Hinni, M.L., Rodrigo, J.P., Rinaldo, A.   +37 more
core   +1 more source

Exploration of Predictive Biomarkers for Postoperative Recurrence in Chronic Rhinosinusitis with Nasal Polyps Based on Serum Multiple-Cytokine Profiling

Mediators of Inflammation, 2022
Background. Functional nasal endoscopic surgery (FESS) is an effective treatment approach for chronic rhinosinusitis with nasal polyps (CRSwNP) patients, but some patients still suffer from postoperative recurrence.
Gang Wang, Huiyuan Zheng, Xiaoqian Chen, Jing Zheng, Jiabin Zhan, Rui Li, Yanyan Qi, Yi Ye, Min Zeng, Xin Wei   +9 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Contents Vol. 31 no. 2 July – December 2016

Philippine Journal of Otolaryngology Head and Neck Surgery, 2020
EDITORIAL 4 The Physician’s Pledge: Promises at Dawn, Passages in Darkness Lapeña JF COMMENTARY 6 On Shoulders of Giants: A Message from an Elder Fellow to New Diplomates Llamanzares TP REVIEW ARTICLE 8 The Effectiveness of ...
Philipp J Otolaryngol Head and Neck Surg
doaj  

Head and neck cancer

Annals of Oncology, 2004
n ...
Licitra L., Locati L. D., Bossi P.
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Genetics of hereditary head and neck paragangliomas

, 2014
Item does not contain fulltextBACKGROUND: The purpose of this study was to give an overview on hereditary syndromes associated with head and neck paragangliomas (HNPGs).
Maier, W., Nederveen, Francien H. van, Ferlito, Alfio, Takes, Robert P., Hensen, E.F., Pellitteri, P.K., Hensen, Erik F., Suárez, Carlos, Maier, Wolfgang, Rinaldo, Alessandra, Kunst, H.P., Rodrigo Tapia, Juan Pablo, Nederveen, F.H. van, Boedeker, Carsten Christof, Rodrigo, Juan P., Takes, R.P., Ferlito, A., Suárez Nieto, Carlos, Pellitteri, Phillip K., van Nederveen, F.H., Kunst, H.P.M., Neumann, H.P., Neumann, Hartmut P. H., Neumann, H.P.H., Suarez, C., Kunst, Henricus P., Boedeker, C.C., Rodrigo, J.P., Rinaldo, A.   +28 more
core   +1 more source

Angiosarcoma of the Head and Neck [PDF]

International Archives of Otorhinolaryngology, 2015
Introduction Angiosarcoma of the head and neck is a rare vascular sarcoma associated with high rates of local recurrence and distant metastasis and a poor prognosis. Objective We describe our experience treating patients with angiosarcoma of the head and neck to evaluate the outcomes, patterns of failure, and current treatments.
Mullins, Brandon, Hackman, Trevor
openaire   +5 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source