Results 61 to 70 of about 742,331 (314)

Pilomatrixoma in the head and neck [PDF]

Brazilian Journal of Otorhinolaryngology, 2009
Universidade Federal de Sao Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Department of Otorhinolaryngology - Head and Neck ...
Neto, José Arruda Mendes, Raposo, Rafael Mônaco, Segalla, Danilo Kanashiro, Leonhardt, Fernando Danelon   +3 more
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic

, 2020
Importance The rapidly expanding novel coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2, has challenged the medical community to an unprecedented degree.
O'Neill, James P., Parker, Noah, Zender, Chad, Chinn, Steven B., Schiff, Bradley A., Moore, Michael G., Davies, Louise, Orloff, Lisa A., Iyer, N. Gopalakrishna, Givi, Babak, Jalisi, Scharukh, Morris, Luc G. T., Clayburgh, Daniel, Nathan, Cherie-Ann   +13 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Evaluation of pure-tone audiometric protocols in vestibular schwannoma screening

Journal of Otology, 2021
The objective was to evaluate the pure-tone audiogram-based screening protocols in VS diagnostics. We retrospectively analyzed presenting symptoms, pure tone audiometry and MRI finding from 246 VS patients and 442 controls were collected to test ...
Matej Vnencak, Elina Huttunen, Antti A. Aarnisalo, Jussi Jero, Katja Liukkonen, Saku T. Sinkkonen   +5 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Complications, Mortality, and Functional Decline in Patients 80 Years or Older Undergoing Major Head and Neck Ablation and Reconstruction

, 2019
Importance Data regarding outcomes after major head and neck ablation and reconstruction in the growing geriatric population (specifically ≥80 years of age) are limited.
Bur, Andrés M., Kass, Jason I., Fernandes, Rui P., Rajasekaran, Karthik, Al-khudari, Samer, Abello, Eric H., Tassone, Patrick, Cave, Taylor B., Wax, Mark K., Abdelmalik, Michael, Huang, Andrew T., Lamarre, Eric D., Vimawala, Swar, Graboyes, Evan M., Higgins, Kevin M., Ryan, Jesse T., Rich, Jason T., McMullen, Caitlin P., Orzell, Susannah C., Fancy, Tanya, Mantravadi, Avinash V., Alwani, Mohamedkazim M., Goldman, Richard A., Kallogjeri, Dorina, Azoulay, Ofer, Subbarayan, Rahul S., Worley, Mitchell L., L’Esperance, Heidi E.   +27 more
core   +1 more source

Iodide-Induced Severe Encephalopathy: A Case Report and Literature Review

Ear, Nose & Throat Journal
A physically independent and mentally competent 61-year-old gentleman was diagnosed with left upper alveolar spindle cell carcinoma. He underwent left infrastructure maxillectomy with reconstruction and had bismuth iodoform paraffin paste packed in the ...
Nur Aida Razuan MB BCh BAO, Ooi Kar Mun MBBS, Sakina Ghauth MBBS and Master of Otorhinolaryngology – Head & Neck, Liew Yew Toong MBBS and Master of Otorhinolaryngology – Head & Neck   +3 more
doaj   +1 more source