Results 71 to 80 of about 1,437,694 (351)

Peripheral Multiple Cytokine Profiles Identified CD39 as a Novel Biomarker for Diagnosis and Reflecting Disease Severity in Allergic Rhinitis Patients

Mediators of Inflammation, 2023
Background. Allergic rhinitis (AR) is a common clinical problem, and immune cells and cytokines were proven to be pivotal in its pathogenesis. Our aim is to measure the peripheral concentrations of multiple cytokines in AR patients and identify novel ...
Yuanwei Jiang, Weiqun Hu, Zhifu Cai, Chaofan Lin, Shengnan Ye   +4 more
doaj   +1 more source

Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer. [PDF]

, 2017
Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown.
Barrett, John W, Black, Morgan, Boutros, Paul C, Datti, Alessandro, Fung, Kevin, Ghasemi, Farhad, Le, Carson Cao Son Huu, Leong, Hon Sing, Lowerison, Matthew R, MacNeil, Danielle, Mymryk, Joe S, Nichols, Anthony C, Palma, David A, Pinto, Nicole, Ruicci, Kara M, Vizeacoumar, Frederick, Winquist, Eric, Yoo, John   +17 more
core   +1 more source

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno, Giovanni Ermanis, Christian Lettieri, Andrea Bernardini, Gaia Pellitteri, Enrico Belgrado, Elena Betto, Gian Luigi Gigli, David De Monte, Marco Domenico Scanni, Marco Mucchiut, Giuseppe Damante, Mariarosaria Valente, Francesco Janes   +13 more
wiley   +1 more source

Distribution of sentinel nodes from parotid tumors–A feasibility study

Cancer Medicine, 2023
Background Optimum management of the N0 neck is unresolved in parotid salivary gland cancer. Sentinel node biopsy (SNB) can reliably detect microscopic lymph node metastasis and its´ clinical use is increasing for head and neck tumors. The object of this
Lalle Hammarstedt‐Nordenvall, Rusana Bark, Alexandra Elliot, Mathias Von Beckerath, Caroline Gahm   +4 more
doaj   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

A Tele-Operated Display With a Predictive Display Algorithm [PDF]

, 2019
Tele-operated display systems with head mounted displays (HMD) are becoming popular as visual feedback systems for tele-operation systems. However, the users are suffered from time-varying bidirectional delays caused by the latency and limited bandwidth ...
Bae, Joonbum, Han, Kyutaek, Jung, Yeongtae   +2 more
core   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

PERBEDAAN SKOR GERIATRIC DEPRESSION SCALE PADA PASIEN USIA LANJUT DENGAN KANKER KEPALA DAN LEHER YANG BELUM DAN SEDANG MENJALANI RADIOTERAPI [PDF]

, 2016
Background. There has been a constant rise in the elderly population number throughout the world, more so in the developing countries. This growth is paralleled with rapid increase in disease prevalence, head and neck cancer being one of them.
Saktini, Fanti, Sekarnegari, Gendis, Wardani, Natalia Dewi   +2 more
core  

Life as an early career researcher: Ruth Bower [PDF]

, 2016
Ruth Bower talks to Francesca Lake, Managing Editor: Ruth is currently researching head and neck cancer chemoradiotherapy regimens utilizing microfluidic technology to maintain and interrogate biopsies.
Bower, Ruth
core   +1 more source