Results 71 to 80 of about 1,585,150 (380)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

The Role of the P1 Latency in Auditory and Speech Performance Evaluation in Cochlear Implanted Children

Neural Plasticity, 2022
Auditory deprivation affects normal age-related changes in the central auditory maturation. Cochlear implants (CIs) have already become the best treatment strategy for severe to profound hearing impairment.
Shan Xiong, Liwei Jiang, Yu Wang, Tao Pan, Furong Ma   +4 more
doaj   +1 more source

Are the demographics for squamous cell cancer in the head and neck changing in the United Kingdom? [PDF]

, 2007
Head and neck squamous cell carcinoma is well known to be more common in men than women. Smoking and alcohol are the key risk factors causing such malignancies and there are several publications which have suggested that the prevalence of these diseases ...
Hassan, MA, Howard, DJ, Lund, VJ, Sackert, AA   +3 more
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Psychosocial interventions for patients with head and neck cancer. [PDF]

, 2013
BACKGROUND: A diagnosis of head and neck cancer, like many other cancers, can lead to significant psychosocial distress. Patients with head and neck cancer can have very specific needs, due to both the location of their disease and the impact of ...
Aaronson, Bai, Bessell, Brink, Coleman, Cosco, Coyne, Doyle, Duffy, Duffy, Easterling, Fan, Fawzy, Fiegenbaum, Folkman, Frampton, Haman, Hammerlid, Harrison, Head, Holland, Holland, Humphris, Katz, Kroenke, Luckett, Maddalena, McLachlan, Mitchell, Norton, Norton, Petruson, Radloff, Rosenberg, Semple, Semple, Semple, Sharma, Sheikh, Spielberger, Spitzer, Vakharia, Veer, Vilela, Watson, Yongqin, Zigmond   +46 more
core   +2 more sources

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)

Journal of Immunotherapy for Cancer, 2019
Head and neck cancers, including those of the lip and oral cavity, nasal cavity, paranasal sinuses, oropharynx, larynx and nasopharynx represent nearly 700,000 new cases and 380,000 deaths worldwide per annum, and account for over 10,000 annual deaths in
E. Cohen, R. Bell, C. Bifulco, B. Burtness, M. Gillison, K. Harrington, Q. Le, Nancy Y. Lee, R. Leidner, Rebecca L. Lewis, L. Licitra, H. Mehanna, L. Mell, A. Raben, A. Sikora, R. Uppaluri, Fernanda Whitworth, D. Zandberg, R. Ferris   +18 more
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

A physical model suggests that hip-localized balance sense in birds improves state estimation in perching: implications for bipedal robots [PDF]

, 2018
In addition to a vestibular system, birds uniquely have a balance-sensing organ within the pelvis, called the lumbosacral organ (LSO). The LSO is well developed in terrestrial birds, possibly to facilitate balance control in perching and terrestrial ...
Darío Urbina-Meléndez, Darío Urbina-Meléndez, Francisco J. Valero-Cuevas, Francisco J. Valero-Cuevas, Kian Jalaleddini, Monica A. Daley   +5 more
core   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Peripheral Multiple Cytokine Profiles Identified CD39 as a Novel Biomarker for Diagnosis and Reflecting Disease Severity in Allergic Rhinitis Patients

Mediators of Inflammation, 2023
Background. Allergic rhinitis (AR) is a common clinical problem, and immune cells and cytokines were proven to be pivotal in its pathogenesis. Our aim is to measure the peripheral concentrations of multiple cytokines in AR patients and identify novel ...
Yuanwei Jiang, Weiqun Hu, Zhifu Cai, Chaofan Lin, Shengnan Ye   +4 more
doaj   +1 more source

Supraclavicular node metastasis presenting with internal jugular vein thrombosis [PDF]

, 1989
A case of internal jugular vein thrombosis secondary to compression by a metastasis in Virchow’s node and the investigations leading to the diagnosis is described.
Brincat, Stephen
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