Results 81 to 90 of about 3,900,516 (357)

A Tele-Operated Display With a Predictive Display Algorithm [PDF]

, 2019
Tele-operated display systems with head mounted displays (HMD) are becoming popular as visual feedback systems for tele-operation systems. However, the users are suffered from time-varying bidirectional delays caused by the latency and limited bandwidth ...
Bae, Joonbum, Han, Kyutaek, Jung, Yeongtae   +2 more
core   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Evaluation of pure-tone audiometric protocols in vestibular schwannoma screening

Journal of Otology, 2021
The objective was to evaluate the pure-tone audiogram-based screening protocols in VS diagnostics. We retrospectively analyzed presenting symptoms, pure tone audiometry and MRI finding from 246 VS patients and 442 controls were collected to test ...
Matej Vnencak, Elina Huttunen, Antti A. Aarnisalo, Jussi Jero, Katja Liukkonen, Saku T. Sinkkonen   +5 more
doaj  

A physical model suggests that hip-localized balance sense in birds improves state estimation in perching: implications for bipedal robots [PDF]

, 2018
In addition to a vestibular system, birds uniquely have a balance-sensing organ within the pelvis, called the lumbosacral organ (LSO). The LSO is well developed in terrestrial birds, possibly to facilitate balance control in perching and terrestrial ...
Darío Urbina-Meléndez, Darío Urbina-Meléndez, Francisco J. Valero-Cuevas, Francisco J. Valero-Cuevas, Kian Jalaleddini, Monica A. Daley   +5 more
core   +3 more sources

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Conversion from Selective to Comprehensive Neck Dissection: Is It Necessary for Occult Nodal Metastasis? 5-Year Observational Study [PDF]

Clinical and Experimental Otorhinolaryngology, 2013
ObjectivesTo compare the therapeutic results between selective neck dissection (SND) and conversion modified radical neck dissection (MRND) for the occult nodal metastasis cases in head and neck squamous cell carcinoma.MethodsForty-four cases with occult
Sun Min Park, Dong Jin Lee, Eun Jae Chung, Jin Hwan Kim, Il Seok Park, Min Joo Lee, Young Soo Rho   +6 more
doaj   +1 more source

Internal strain regulates the nucleotide binding site of the kinesin leading head [PDF]

PNAS (2007) vol 104, 2175-2180, 2007
In the presence of ATP, kinesin proceeds along the protofilament of microtubule by alternated binding of two motor domains on the tubulin binding sites. Since the processivity of kinesin is much higher than other motor proteins, it has been speculated that there exists a mechanism for allosteric regulation between the two monomers.
arxiv   +1 more source

Mechatronic design of the Twente humanoid head [PDF]

, 2010
This paper describes the mechatronic design of the Twente humanoid head, which has been realized in the purpose of having a research platform for human-machine interaction.
Brouwer, Dannis M., Carloni, Raffaella, Reilink, Rob, Stramigioli, Stefano, Visser, Ludo C.   +4 more
core   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Asymptotic analysis of the Narrow Escape Problem in general shaped domain with several absorbing necks [PDF]

arXiv, 2023
This paper considers the two-dimensional narrow escape problem in a domain which is composed of a relatively big head and several thin necks. The narrow escape problem is to compute the mean first passage time(MFPT) of a Brownian particle traveling from inside the head to the end of the necks.
arxiv