Results 121 to 130 of about 315,615 (312)

Medial sural artery perforator free flap for small- to medium-sized defects in head and neck reconstruction: a suitable replacement for radial forearm free flap

Maxillofacial Plastic and Reconstructive Surgery
Background and objectives To compare clinical outcomes and donor site morbidity between medial sural artery perforator (MSAP) flap and radial forearm free (RFF) flap for soft tissue reconstruction of head and neck.
Yulian Zhang, Keran Pan, Jian Wu, Xi Tang   +3 more
doaj   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

Quality of life in patients with head and neck cancer receiving targeted or multimodal therapy - Update of the EORTC QLQ-H&N35, Phase I.

, 2012
BACKGROUND: The objective of this study was to identify relevant quality of life (QOL) issues in patients with head and neck cancer receiving multimodal and/or targeted therapies.
de Leeuw, I.M.; id_orcid, Guntinas-Lichius, O., Langendijk, Johannes A., Pinto, Monica, Sherman, Allen C, Zotti, Paola, Sen, M., Zotti, P., Yarom, N., Yarom, Noam, EORTC Head Neck Canc Grp, Spiegel, Karin, Nicolatou-Galitis, Ourania, Langendijk, J.A., Hammerlid, E., Sherman, A.C., Galalae, Razvan, Singer, Susanne;Arraras, Juan I.;Baumann, Ingo;Boehm, Andreas;Chie, Wei-Chu;Galalae, Razvan;Langendijk, Johannes A.;Guntinas-Lichius, Orlando;Hammerlid, Eva;Pinto, Monica;Nicolatou-Galitis, Ourania;Schmalz, Claudia;Sen, Mehmet;Sherman, Allen C.;Spiegel, Karin;Verdonck-de Leeuw, Irma;Yarom, Noam;Zotti, Paola;Hofmeister, Dirk, Spiegel, Karine, Singer, S., Boehm, A., Hofmeister, Dirk, Spiegel, K., Chie, W-C, Arraras, J.I., Singer, Susanne, Guntinas-Lichius, Orlando, Schmalz, Claudia, Arraras, J I, Langendijk, Johannes A.; id_orcid, Baumann, Ingo, Langendijk, Johannes A, Chie, Wei-Chu, Schmalz, C., EORTC Quality Life Grp, Baumann, I, Boehm, Andreas, Chie, W.C., Sherman, Allen C., on behalf of the EORTC Quality of Life and the EORTC Head and Neck Cancer Groups, Pinto, M., Galalae, R., Hofmeister, D., Nicolatou-Galitis, O., Hammerlid, Eva, Hammerlid, E, Verdonck-de Leeuw, Irma, de Leeuw, I.M., Arraras, Juan I., Sen, Mehmet, 季瑋珠   +50 more
core   +1 more source

Correction: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma

Journal of Experimental & Clinical Cancer Research, 2022
Xin Zhu, Jia-jie Xu, Si-si Hu, Jian-guo Feng, Lie-hao Jiang, Xiu-xiu Hou, Jun Cao, Jing Han, Zhi-qiang Ling, Ming-hua Ge   +9 more
doaj   +1 more source

Predictive risk-scoring model for lateral lymph node metastasis in papillary thyroid carcinoma

Scientific Reports
This study aims to evaluate candidate risk factors for lateral lymph node metastasis (LLNM) and develop a predictive model to identify high-risk groups among patients with papillary thyroid carcinoma (PTC).
Yehao Guo, Yunye Liu, Weidong Teng, Yan Pan, Lizhuo Zhang, Dongdong Feng, Jiajun Wu, Wenli Ma, Jiafeng Wang, Jiajie Xu, Chuanming Zheng, Xuhang Zhu, Zhuo Tan, Liehao Jiang   +13 more
doaj   +1 more source

EBV-positive small cell neuroendocrine carcinoma of the nasopharynx with cervical lymph node metastasis: a case report and literature review

Frontiers in Oncology
PurposeInvestigating the diagnosis and treatment of Epstein-Barr virus-positive small cell neuroendocrine carcinomas of the nasopharynx with cervical lymph node metastasis.MethodsThe clinical data of a patient with Epstein-Barr virus-positive small cell ...
Jincai Xue, Wenjuan Ma, Xudong Liu, Yunsheng Wang, Xingyue Wang, Zhihu Li, Youxin Tian, Qinjiang Liu, Fang Dong   +8 more
doaj   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Unveiling Prescribing Patterns: A Systematic Review of Chronic Opioid Prescriptions After Head and Neck Cancer Surgeries

Objective: This study aims to review opioid prescribing changes for pain management in head and neck cancer (HNC) surgery patients, given the recent focus on Enhanced Recovery After Surgery protocols. Data sources: MEDLINE, Embase, and CENTRAL, covering
Karki, Sabin, Ramirez, Mirian, Sim, Michael W., Yesensky, Jessica A., Mantravadi, Avinash, Campbell, David A., Stephanian, Brooke, Chen, Diane W., Farlow, Janice L., Moore, Michael G.   +9 more
core   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Oncogenomics/Proteomics of Head and Neck Cancer

, 2018
Head and neck squamous cell carcinomas (HNSCC) develop in the mucosal linings of the upper aerodigestive tract. Despite the fact that the disease develops in a single tissue in a relatively small anatomical region, it is remarkably heterogeneous.
Brakenhoff, Ruud H.
core   +1 more source