Results 121 to 130 of about 557,930 (311)

Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer [PDF]

, 2012
Background To evaluate the feasibility of image-guided radiotherapy based on helical Tomotherapy to spare the contralateral parotid gland in head and neck cancer patients with unilateral or no neck node metastases.
Abraham, Dave, Ceizyk, Misty, Chi, Alexander, Desai, Anand, Hamilton, Russ, Jang, Siyoung, Karlsson, Ulf, Krafft, Shane P, NC DOCKS at East Carolina University, Nguyen, Nam P, Slane, Benjamin, Smith-Raymond, Lexie, Stevie, Michelle, Vinh-Hung, Vincent, Vos, Paul   +14 more
core   +3 more sources

CANCER OF THE HEAD AND NECK

Journal of the American Medical Association, 1948
III. CANCER OF THE LARYNX Anatomically the larynx extends from the tip of the epiglottis to the inferior margin of the cricoid cartilage, and the term cancer of the larynx, therefore, includes all malignant growths arising in the epiglottis, the aryepiglottic folds, the arytenoids, the ventricular bands, the ventricles, the vocal cords, the subglottic
openaire   +3 more sources

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Updated Clinical Considerations for Dental Implant Therapy in Irradiated Head and Neck Cancer Patients [PDF]

, 2013
An increasing number of reports indicate successful use of dental implants (DI) during oral rehabilitation for head and neck cancer patients undergoing tumor surgery and radiation therapy.
Chan, Hsun‐liang, MacEachern, Mark, Oh, Tae‐ju, Tanaka, Takako Imai, Tindle, David Ira   +4 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

5-Aza-2′-deoxycytidin (Decitabine) increases cancer-testis antigen expression in head and neck squamous cell carcinoma and modifies immune checkpoint expression, especially in CD39-positive CD8 and CD4 T cells

Neoplasia: An International Journal for Oncology Research
Failure of immunotherapy in head and neck squamous cell carcinoma (HNSCC) patients represents an unmet need to augment leverage of adaptive immunity. Immunogenic cancer-testis antigen (CTA) expression as well as lymphocyte differentiation and function ...
Adrian Fehn, Adrian von Witzleben, Ayla Grages, Tsima Abou Kors, Jasmin Ezić, Annika C. Betzler, Cornelia Brunner, Patrick J. Schuler, Marie-Nicole Theodoraki, Thomas K. Hoffmann, Simon Laban   +10 more
doaj   +1 more source

Metal concentrations in hair of patients with various head and neck cancers as a diagnostic aid [PDF]

, 2015
Head and neck cancers are one of the most frequent cancers worldwide. This paper attempts to evaluate disturbances of homeostasis of the necessary elements (calcium, magnesium, zinc, copper, iron, manganese) and changes in the levels of toxic metals ...
Baralkiewicz, Danuta, Florek, Ewa, Golasik, Magdalena, Golusiński, Wojciech, Herman, Małgorzata, Napierała, Marta, Piekoszewski, Wojciech, Szyfter, Krzysztof, Szyfter, Witold, Walas, Stanisław, Woźniak, Anna   +10 more
core   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Medial sural artery perforator free flap for small- to medium-sized defects in head and neck reconstruction: a suitable replacement for radial forearm free flap

Maxillofacial Plastic and Reconstructive Surgery
Background and objectives To compare clinical outcomes and donor site morbidity between medial sural artery perforator (MSAP) flap and radial forearm free (RFF) flap for soft tissue reconstruction of head and neck.
Yulian Zhang, Keran Pan, Jian Wu, Xi Tang   +3 more
doaj   +1 more source

Electronic swallowing intervention package to support swallowing function in patients with head and neck cancer: development and feasibility study [PDF]

, 2018
Background: Many patients undergoing treatment for head and neck cancer (HNC) experience significant swallowing difficulties, and there is some evidence that swallowing exercises may improve outcomes, including quality of life.
Boa, Sally, Cairns, David, Cowie, Julie, King, Emma, Wells, Mary   +4 more
core   +2 more sources