Results 71 to 80 of about 581,430 (272)
Cell Reports, 2020 Summary: The retrosplenial cortex (RSC) is essential for memory and navigation, but the neural codes underlying these functions remain largely unknown.
Ellen K.W. Brennan +4 more
doaj +1 more source
Encoding of 3D head direction information in the human brain
, 2019 Head direction cells are critical for navigation because they convey information about which direction an animal is facing within an environment. To date, most studies on head direction encoding have been conducted on a horizontal two-dimensional (2D ...
Kim, M., Maguire, E.
core +1 more source
Multimodal Representation of Space in the Posterior Parietal Cortex and its use in Planning Movements [PDF]
, 1997 Recent experiments are reviewed that indicate that sensory signals from many modalities, as well as efference copy signals from motor structures, converge in the posterior parietal cortex in order to code the spatial locations of goals for movement ...
Andersen, Richard A. +3 more
core +1 more source
Uncoupling of dysgranular retrosplenial “head direction” cells from the global head direction network [PDF]
, 2016 Abstract Spatial cognition is an important model system with which to investigate how sensory signals are transformed into cognitive representations. Head direction cells, found in several cortical and subcortical regions, fire when an animal faces a given direction and express a global directional signal which is anchored by visual ...
Jacob, Pierre-Yves +5 more
openaire +1 more source
Angular head velocity cells within brainstem nuclei projecting to the head direction circuit
The Journal of Neuroscience, 2023 Abstract An animal’s perceived sense of orientation depends upon the head direction (HD) system found in several limbic structures and depends upon an intact peripheral vestibular labyrinth. However, how the vestibular system influences the generation, maintenance, and updating of the HD signal remains poorly understood.
Jalina A. Graham +9 more
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Neural encoding of large-scale three-dimensional space – properties and constraints
Frontiers in Psychology, 2015 How the brain represents represent large-scale, navigable space has been the topic of intensive investigation for several decades, resulting in the discovery that neurons in a complex network of cortical and subcortical brain regions co-operatively ...
Kate J Jeffery +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Precise coupling of the thalamic head-direction system to hippocampal ripples
Nature Communications, 2020 Thalamic head direction (HD) cells are necessary to establish spatial maps in the hippocampus. Here, the authors show that HD cells tuned to a particular direction are coupled to individual hippocampal ripple events during sleep, suggesting an influence ...
Guillaume Viejo, Adrien Peyrache
doaj +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source