Results 51 to 60 of about 3,322,345 (245)

A Technique of Forced Expiratory Noise Time Evaluation Provides Distinguishing Human Pulmonary Ventilation Dynamics During Long-Term Head-Down and Head-Up Tilt Bed Rest Tests Simulating Micro and Lunar Gravity

Frontiers in Physiology, 2018
Estimating the effect of microgravity/hypogravity on pulmonary ventilation function remains topical. Recently developed acoustic techniques based on the evaluation of the forced expiratory noise time (FETa) were hypothesized to be a promising tool for ...
Veronika V. Malaeva, Vladimir I. Korenbaum, Irina A. Pochekutova, Anatoly E. Kostiv, Svetlana N. Shin, Vladimir P. Katuntsev, Viktor M. Baranov   +6 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Impact of Daily Lower‐Body Negative Pressure or Cycling Followed by Venous Constrictive Thigh Cuffs on Bedrest‐Induced Orthostatic Intolerance

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Orthostatic intolerance occurs following immobilization in patients on Earth and in astronauts after spaceflight. Head‐down tilt bedrest is a terrestrial model for weightlessness and induces orthostatic intolerance.
Jan‐Niklas Hönemann, Fabian Hoffmann, Laura de Boni, Peter Gauger, Edwin Mulder, Stefan Möstl, Karsten Heusser, Marie‐Therese Schmitz, Marcel Halbach, Steven S. Laurie, Stuart M. C. Lee, Brandon R. Macias, Jens Jordan, Jens Tank   +13 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Limited Effect of 60-Days Strict Head Down Tilt Bed Rest on Vascular Aging

Frontiers in Physiology, 2021
BackgroundCardiovascular risk may be increased in astronauts after long term space flights based on biomarkers indicating premature vascular aging. We tested the hypothesis that 60 days of strict 6° head down tilt bed rest (HDTBR), an established space ...
Stefan Möstl, Stefan Orter, Fabian Hoffmann, Fabian Hoffmann, Martin Bachler, Bernhard Hametner, Siegfried Wassertheurer, Jérémy Rabineau, Edwin Mulder, Bernd Johannes, Jens Jordan, Jens Jordan, Jens Tank   +12 more
doaj   +1 more source

Fractal analysis of cytoskeleton rearrangement in cardiac muscle during head-down tilt

, 1996
Thomason, Donald B., Otis Anderson III, and Vandana Menon.Fractal analysis of cytoskeleton rearrangement in cardiac muscle during head-down tilt. J. Appl. Physiol.
Vandana Menon, Otis Anderson, Donald B. Thomason   +2 more
core   +1 more source

Cohen et al. Supplemental Figure 1: Arterial and venous blood flow patterns in response to postural tilt

, 2023
Supplemental Figure 1: Representative Doppler tracings of a 30-year-old male participant. In each condition, tracings are presented for each vessel by aligning electrocardiogram R-waves.
Jason Au (6893915), Rose Samra (16414378), Jeremy Cohen (16414377)   +2 more
core   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Functional Cardiac Adaptation to 60 Days Strict Head-Down-Tilt Bedrest

, 2020
Background: Reduced physical activity increases the risk for heart failure. Myocardial strain measurements capture subtle abnormalities in myocardial function.
Tank, Jens, Johannes, B., Rabineau, J., Mehrkens, D., Caiania, E.G., Migeotte, P.-F., Hoffmann, F., Jordan, J, Enrico G Caiania, Jens Jordan, Dennis Mehrkens, Fabian Hoffmann, Jeremy Rabineau, Bernd W Johannes, Pierre-Francois Migeotte, Jens Tank   +15 more
core   +1 more source