Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Effect of anticoagulation on isolated traumatic brain injury mortality using TQIP database: a propensity score analysis stratified by head injury severity. [PDF]
Kulvatunyou N +9 more
europepmc +1 more source
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Comparing the kinematics related to inflicted head injury between violent shaking of a 6-week-old and a 1-year-old infant surrogate. [PDF]
Hutchinson K +4 more
europepmc +1 more source
Evaluation of the Traumatic Coma Data Bank Computed Tomography Classification for Severe Head Injury
Jim van Os +4 more
openalex +2 more sources
Cognitive recovery after severe head injury. 2. Wechsler Adult Intelligence Scale during post-traumatic amnesia. [PDF]
Ian Mandleberg
openalex +1 more source
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti +11 more
wiley +1 more source
Adolescent trauma and alcohol: increased risk for severe head injury and organ dysfunction-insights from the TraumaRegister DGU<sup>®</sup>. [PDF]
Hörauf JA +7 more
europepmc +1 more source

