Results 21 to 30 of about 487,096 (219)

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway

iScience
Summary: Both therapeutic hypothermia and neural stem cells (NSCs) transplantation have shown promise in neuroprotection and neural repair after brain injury.
Yuxiao Ma, Zhenghui He, Jiangchang Wang, Ping Zheng, Zixuan Ma, Qian Liang, Qiao Zhang, Xiongfei Zhao, Jialin Huang, Weiji Weng, Jiyao Jiang, Junfeng Feng   +11 more
doaj   +1 more source

Contrecoup Head Injury

Indian Journal of Neurosurgery, 2017
Contrecoup injuries comprise a group of focal brain injuries that occur at areas distant from the point of impact. It has been hypothesized that patients with contrecoup injuries would have a worse outcome because of the diffuse nature of injury.
Manpreet Singh Banga, Sandeep BV, Kaushik Roy, Suniti Kumar Saha, Sourabh Dixit, Partha Ghosh   +5 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

The effect of football (soccer) heading on gross and fine motor control in women

Frontiers in Sports and Active Living
IntroductionHeading is an integral component of football, but concerns remain about its impact on brain health. This study examines the acute effects of heading on gross and fine motor control as a measure of the motor-cognitive function of women ...
Jac L. Palmer, Bert Bond, Bert Bond, Alex Woodgates, Alex Woodgates, Jacob Jack, Jacob Jack, Oliver Smail, Oliver Smail, Ryan Baker, Genevieve Williams   +10 more
doaj   +1 more source

Predictive Value of Non-Invasive Intracranial Pressure Monitoring in Profoundly Impaired Traumatic Brain Injury Patients

Babali Nursing Research, 2023
Introduction: Trauma brain injury is an emergency condition that requires immediate precise first aid to reduce mortality rates and prevent secondary complications.
Barkah Waladani, Putra Agina Widyaswara Suwaryo, Isma Yuniar, Podo Yuwono, Endah Setianingsih   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Fenofibrate alleviates the brain edema after traumatic brain injury by enhancing endothelial OXPHOS

Redox Biology
Traumatic brain injury (TBI) frequently leads to brain edema, a life-threatening complication and a major cause of mortality and disability. Here, we report that fenofibrate (FFB), an agonist of the nuclear receptor peroxisome proliferator-activated ...
Qiyuan Feng, Yingwei Gao, Xiaokun Gu, Xinxin Zhao, Xinwen Liu, Zixuan Ma, Wenlan Qi, Zhenghui He, Yuhan Han, Jian Zhang, Wenye Wang, Zhifan Li, Daiwen Zhang, Jialin Huang, Yong Lin, Jiyuan Hui, Bayasgalan Onondari, Galbadrakh Erdenetsetseg, Qing Mao, Jiyao Jiang, Yan Zhou, Weiji Weng, Yan Zhang, Junfeng Feng   +23 more
doaj   +1 more source

Limiting Performance of Helmets for the Prevention of Head Injury

Shock and Vibration, 1999
This is a study of the theoretical optimal (limiting) performance of helmets for the prevention of head injury. A rigid head injury model and a two-mass translational head injury model are employed.
Z.Q. Cheng, W.D. Pilkey, J.R. Crandall, C.R. Bass, K. Darvish   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source