Results 321 to 330 of about 4,378,273 (391)

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Lifetime history of head injury is associated with reduced perivascular space number in acute mild traumatic brain injury. [PDF]

Brain Commun
Garcia KJ, Brolly G, Ng D, Bederson M, Martinez P, Whiting MD.   +5 more
europepmc   +1 more source

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

Advanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li, Bo Ma, Jia‐Wei Lu, Kai‐Chao Zhang, Chao Ma, Sheng‐Feng Bai, Yan‐Jiao Li, Si‐Qi Ying, Wei‐Zong Weng, Kai Zhang, Xi‐Wang Hu, Rang Li, Chen‐Xi Zheng, Xiao‐Ru Xu, Ji Chen, Fang Jin, Hao‐Kun Xu, Jian‐Wei Xie, Yan Jin, Yi Shuai, Bing‐Dong Sui   +20 more
wiley   +1 more source

Stiffness‐Tunable Neurotentacles for Minimally Invasive Implantation and Long‐Term Neural Activity Recordings

Advanced Science, EarlyView.
A hydraulically actuated “Neurotentacle” probe offers tunable stiffness for precise implantation into the deep brain without rigid shuttles or dissolvable coatings. It stiffens during insertion to penetrate tissue and softens afterward to minimize damage and enable stable long‐term recordings.
Yang Wang, Xing Xu, Xiaowei Yang, Rongyu Tang, Ying Chen, Shan Zang, Yijun Wang, Jing Liang, Weihua Pei   +8 more
wiley   +1 more source

Severe head injury in children: Management of a traumatic craniotomy case in a resource-constrained hospital. [PDF]

Int J Surg Case Rep
Essobiyou TB, Labou AK, Ouedraogo SSL, Diendere PRC, Kpelao SE.   +4 more
europepmc   +1 more source

Rapid Amplification of Cerebrospinal Fluid Pressure as a Possible Mechanism for Optic Nerve Sheath Bleeding in Infants With Nonaccidental Head Injury. [PDF]

Invest Ophthalmol Vis Sci
Stewart PS, Brook BS, Jensen OE, Spelman TA, Whittaker RJ, Zouache MA.   +5 more
europepmc   +1 more source

Changes in cerebral vascular reactivity following mild repetitive head injury in awake rats: modeling the human experience. [PDF]

Exp Brain Res
Bens N, Kulkarni P, Ferris CF.
europepmc   +1 more source

Comparative Analysis of "Trauma and Injury Severity Scores" and "Madras Head Injury Prognostic Scale" in Assessing Head Trauma Prognosis in the Emergency Department of Shahid Beheshti Hospital, Sabzevar, Iran. [PDF]

Bull Emerg Trauma
Hamidnezhad M, Ansari M, Afshari Saleh T, Foji S.   +3 more
europepmc   +1 more source

Computed Tomographic Scan for Head Injury Patients: Any Justification for Adapting Routine Cranio-Cervical Examination Irrespective of Clinical Severity? [PDF]

J West Afr Coll Surg
Muhammad IH, Saleh MK, Adamu MY, Ismail A.   +3 more
europepmc   +1 more source

Head Kinematics Associated with Off-Field Head Injury Assessment (HIA1) Events in a Season of English Elite-Level Club Men's and Women's Rugby Union Matches. [PDF]

Sports Med
Allan D, Tooby J, Starling L, Tucker R, Falvey É, Salmon D, Brown J, Hudson S, Stokes K, Jones B, Kemp S, O'Halloran P, Cross M, Bussey M, Tierney G.   +14 more
europepmc   +1 more source