Results 41 to 50 of about 3,249,670 (256)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Listener head gestures and verbal feedback expressions in a distraction task [PDF]

, 2012
Wlodarczak M, Buschmeier H, Malisz Z, Kopp S, Wagner P. Listener head gestures and verbal feedback expressions in a distraction task. In: Proceedings of the Interdisciplinary Workshop on Feedback Behaviors in Dialog, INTERSPEECH2012 Satellite Workshop ...
Wagner, Petra ; https://orcid.org/, Kopp, Stefan ; https://orcid.org/, Wlodarczak, Marcin, Buschmeier, Hendrik ; https://orcid.org/, Malisz, Zofia   +4 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Data_Sheet_2_Head-Movement-Emphasized Rehabilitation in Bilateral Vestibulopathy.PDF

, 2018
Objective: Although there is evidence that vestibular rehabilitation is useful for treating chronic bilateral vestibular hypofunction (BVH), the mechanisms for improvement, and the reasons why only some patients improve are still unclear.
Alexander G. Knorr (5522216), Silvy Kellerer (5522219), Cornelia Schlick (618774), Maria Heuberger (551541), Cecilia Ramaioli (647462), Nadine Lehnen (496901), Erich Schneider (551545), Klaus Jahn (551544)   +7 more
core   +1 more source

A Phase-based Approach to Rightward Movement in Comparatives [PDF]

, 2008
In this article, I aim at providing a phase-based explanation of extraposition phenomena in attributive comparatives. Conforming to a semantic requirement, the than-expression is an obligatory complement of the functional Degree head. However, there is
Kántor, Gergely
core   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Learning the optimal control of coordinated eye and head movements [PDF]

, 2011
Various optimality principles have been proposed to explain the characteristics of coordinated eye and head movements during visual orienting behavior.
Saeb, Sohrab, Triesch, Jochen, Sohrab Saeb, Weber Cornelius, Jochen Triesch, Triesch Jochen, Weber, Cornelius, Cornelius Weber, Saeb Sohrab   +8 more
core   +1 more source

A Public Database of Immersive VR Videos with Corresponding Ratings of Arousal, Valence, and Correlations between Head Movements and Self Report Measures

Frontiers in Psychology, 2017
Virtual reality (VR) has been proposed as a methodological tool to study the basic science of psychology and other fields. One key advantage of VR is that sharing of virtual content can lead to more robust replication and representative sampling.
Benjamin J. Li, Jeremy N. Bailenson, Adam Pines, Walter J. Greenleaf, Leanne M. Williams   +4 more
doaj   +1 more source