Results 101 to 110 of about 803,099 (294)

Clinical experience with transcutaneous supraorbital nerve stimulation in patients with refractory migraine or with migraine and intolerance to topiramate: a prospective exploratory clinical study

BMC Neurology, 2017
Background Migraine is included in the top-ten disabling diseases and conditions among the Western populations. Non-invasive neurostimulation, including the Cefaly® device, for the treatment of various types of pain is a relatively new field of interest.
Michail Vikelis, Emmanouil V. Dermitzakis, Konstantinos C. Spingos, Georgios G. Vasiliadis, George S. Vlachos, Evaggelia Kararizou   +5 more
doaj   +1 more source

HEADACHE AND HYPERTENSION [PDF]

, 1953
I M Stewart
openalex   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

Predicting treatment response using pharmacy register in migraine

The Journal of Headache and Pain, 2019
Background Precision medicine may offer new strategies to treat migraine, and access to existing large cohorts may be a key resource to increase statistical power.
Thomas Folkmann Hansen, Mona Ameri Chalmer, Thilde Marie Haspang, Lisette Kogelman, Jes Olesen   +4 more
doaj   +1 more source

LUMBAR-PUNCTURE HEADACHE [PDF]

, 1950
Jason Marshall
openalex   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Vascular responses to molecular migraine triggers: a systematic review of magnetic resonance angiography studies

The Journal of Headache and Pain
Objective To synthesize and interpret magnetic resonance angiography (MRA) findings on vascular changes after administration of established molecular migraine triggers in adults with migraine and in healthy individuals, focusing on the middle meningeal ...
Robin Arquizan, Anna G. Melchior, Rune H. Christensen, Haidar M. Al-Khazali, Messoud Ashina, Håkan Ashina   +5 more
doaj   +1 more source

Observations on Megrim or Sick-Headache [PDF]

, 1872
E. Liveing
openalex   +1 more source

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

"LOWER HALF HEADACHE" (NEURALGIC) OF NASAL ORIGIN [PDF]

, 1922
Greenfield Sluder
openalex   +1 more source