PACAP38-induced migraine attacks are independent of CGRP signaling: a randomized controlled trial [PDF]
The Journal of Headache and PainBackground Calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) are key pathogenic drivers of migraine.
Mohammad Al-Mahdi Al-Karagholi +4 more
doaj +2 more sources
Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1898-1909, December 2022., 2022 Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima +9 more
wiley +1 more source
Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1918-1925, December 2022., 2022 Abstract Objective Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. Methods We performed a retrospective study of patients with NMOSD based on the Wingerchuk 2006 or the revised Wingerchuk 2015 criteria ...
Qin Du +7 more
wiley +1 more source
Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022 Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao +8 more
wiley +1 more source
Associations between stress and migraine and tension-type headache: Results from a school-based study in adolescents from grammar schools in Germany [PDF]
, 2011 Introduction: Stress is considered the major contributor to migraine and tension-type headache in adolescents. Previous studies have focused on general stressors, whereas the aim of the present study was to investigate associations between individuals ...
Blaschek, Astrid +7 more
core +1 more source
Correction: Uncovering drug targets for cluster headache through proteome-wide Mendelian randomization analysis [PDF]
The Journal of Headache and PainZhonghua Xiong +12 more
doaj +2 more sources
Assessment of acute headache in adults - what the general physician needs to know. [PDF]
, 2018 Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal +9 more
core +1 more source
BMC Neurology, 2021 Background We aim to describe and compare patients and general practitioners’ opinions about the different variables related to acute and preventive treatment for migraine. Patients and methods An observational descriptive study was performed.
Javier Trigo-López +6 more
doaj +1 more source
Headache and alexithymia in children and adolescents: what Is the connection? [PDF]
, 2018 Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders.
Calderoni, D +5 more
core +3 more sources
Migraine during COVID-19: Data from Second Wave Pandemic in an Italian Cohort
Brain Sciences, 2021 Objectives: The study aims to assess the impact of the second COVID-19 pandemic wave on migraine characteristics. Methods: This is an observational cross-sectional study conducted on migraine patients previously interviewed during the first Italian ...
Eleonora Gentile +23 more
doaj +1 more source