Results 31 to 40 of about 825,755 (335)

Fremanezumab for the Preventive Treatment of Chronic Migraine. [PDF]

open access: yes, 2017
BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine.
Aycardi, Ernesto   +9 more
core   +2 more sources

Menstrual migraine is caused by estrogen withdrawal: revisiting the evidence

open access: yesThe Journal of Headache and Pain, 2023
Objective To explore and critically appraise the evidence supporting the role of estrogen withdrawal in menstrual migraine. Main body Menstrual migraine, impacting about 6% of reproductive-age women, manifests as migraine attacks closely related to the ...
Bianca Raffaelli   +5 more
doaj   +1 more source

Features of aura in paediatric migraine diagnosed using the ICHD 3 beta criteria [PDF]

open access: yes, 2017
Background In children and adolescents, the prevalence rate of migraine with aura is 1.6%. Few studies concerning migraine with aura features in paediatric population have been reported.
Balestri, Martina   +7 more
core   +1 more source

Occipital Nerve Stimulation in Chronic Migraine: The Relationship Between Perceived Sensory Quality, Perceived Sensory Location, and Clinical Efficacy—A Prospective, Observational, Non-Interventional Study

open access: yesPain and Therapy, 2020
Introduction Occipital nerve stimulation (ONS) is used to treat therapy-resistant chronic migraine. Clinical use has resulted in a wide intraindividual and interindividual variation of clinical efficacy.
Carl H. Göbel   +8 more
doaj   +1 more source

Clinical Features of Pediatric Idiopathic Intracranial Hypertension and Applicability of New ICHD-3 Criteria [PDF]

open access: yes, 2018
Idiopathic intracranial hypertension (IIH) is characterized by intracranial pressure >28 cmH2O in the absence of identifiable causes. Aim of this paper is to describe the clinical phenotype of pediatric IIH and to analyze the applicability of ICHD-3 ...
Barbara Battan   +8 more
core   +2 more sources

Frequent mild head injury promotes trigeminal sensitivity concomitant with microglial proliferation, astrocytosis, and increased neuropeptide levels in the trigeminal pain system. [PDF]

open access: yes, 2017
BACKGROUND: Frequent mild head injuries or concussion along with the presence of headache may contribute to the persistence of concussion symptoms. METHODS: In this study, the acute effects of recovery between mild head injuries and the frequency of ...
Assari, Soroush   +4 more
core   +2 more sources

Headache and alexithymia in children and adolescents: what Is the connection? [PDF]

open access: yes, 2018
Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders.
Calderoni, D   +5 more
core   +3 more sources

In search of a gold standard patient-reported outcome measure to use in the evaluation and treatment-decision making in migraine prevention. A real-world evidence study

open access: yesThe Journal of Headache and Pain, 2021
Background Patient-Reported Outcomes (PROs) have been developed to numerically quantify disability, impact and quality of life. They have been widely used in migraine clinical trials.
Alicia Alpuente   +4 more
doaj   +1 more source

Refractory chronic migraine. a consensus statement on clinical definition from the European Headache Federation [PDF]

open access: yes, 2014
The debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse ...
C. Lampl   +8 more
core   +2 more sources

Clinical characteristics of nummular headache and differentiation between spontaneous and posttraumatic variant: an observational study

open access: yesThe Journal of Headache and Pain, 2019
Background Head trauma has been described as a precipitating event in Nummular Headache (NH). We aimed to describe the largest NH published series and compare characteristics between idiopathic and post-traumatic cases.
Javier Trigo   +5 more
doaj   +1 more source

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