Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
Self-efficacy and medicine use for headache among adolescents in Italy: results from the Italian HBSC 2010 study [PDF]
This article aims first to investigate gender patterns in medicine use, and corresponding headache complaints, in Italian adolescents; second, to examine the association between self-efficacy and medicine use for headache.
Cavallo, Franco+3 more
core +1 more source
Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks
Around 91% of migraine patients use over-the-counter medicines to treat attacks, often without further treatment or medical consultation. This therapeutic principle is established in most countries, regardless of how the healthcare system is otherwise ...
Carl H. Göbel+3 more
doaj +1 more source
The Impact of Biseasonal Time Changes on Migraine
Background: Changes in the daily rhythm can trigger migraine attacks. The sensitivity for triggering attacks is closely linked to the regulation of biological rhythms controlled by the hypothalamus.
Carl H. Göbel+4 more
doaj +1 more source
Understanding patient complaint characteristics using contextual clinical BERT embeddings [PDF]
In clinical conversational applications, extracted entities tend to capture the main subject of a patient's complaint, namely symptoms or diseases. However, they mostly fail to recognize the characterizations of a complaint such as the time, the onset, and the severity.
arxiv
Fremanezumab for the Preventive Treatment of Chronic Migraine. [PDF]
BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine.
Aycardi, Ernesto+9 more
core +2 more sources
Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao+34 more
wiley +1 more source
Using natural language processing to extract health-related causality from Twitter messages [PDF]
Twitter messages (tweets) contain various types of information, which include health-related information. Analysis of health-related tweets would help us understand health conditions and concerns encountered in our daily life. In this work, we evaluated an approach to extracting causal relations from tweets using natural language processing (NLP ...
arxiv +1 more source
Migraine, headache, and mortality in women: a cohort study [PDF]
Background: Migraine carries a high global burden, disproportionately affects women, and has been implicated as a risk factor for cardiovascular disease. Migraine with aura has been consistently associated with increased risk of cardiovascular mortality.
Buring, Julie Elizabeth+3 more
core +1 more source
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita+7 more
wiley +1 more source