Results 101 to 110 of about 17,542 (270)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Grey-Level Cooccurrence Matrix Performance Evaluation For Heading Angle Estimation Of Moveable Vision System In Static Environment [PDF]

open access: yes, 2013
A method of extracting information in estimating heading angle of vision system is presented. Integration of grey-level cooccurrence matrix (GLCM) in an area of interest selection is carried out to choose a suitable region that is feasible for optical ...
Mustafa, Mohd Marzuki   +2 more
core   +1 more source

Remote Estimation of Above-Ground Biomass Throughout the Entire Growth Period for Crops with Conspicuous Spikes

open access: yesRemote Sensing
Above-ground biomass (AGB) is an important factor in crop yield. However, most AGB estimation methods for crops with conspicuous spikes, such as rice and sorghum, can achieve high accuracy during the vegetative stage but low accuracy during the ...
Qiaoling Zhang   +10 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Heading-determination using the Sensor-fusion Based Maritime PNT Unit [PDF]

open access: yes, 2012
This paper presents the heading determination technique with the concept of DLR maritime PNT Unit. By analyzing the characteristics of individual existing heading sensors, a sensor-fusion based heading-determination system according to the concept of DLR
Alexander Born   +7 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Standard deviation of direction specific biases by subject for the visual, vestibular, and spoken heading estimation conditions. [PDF]

open access: yes, 2013
Standard deviation of direction specific biases by subject for the visual, vestibular, and spoken heading estimation conditions.
Benjamin T. Crane (295328)
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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