Results 91 to 100 of about 14,560,647 (251)

Identification of Stable QTLs and Candidate Genes for Heading Date in Wheat Using a 55K SNP-Genotyped Doubled Haploid Population

Agronomy
Heading date (HD) is a key adaptive trait determining wheat regional suitability, yield stability, and resilience to environmental stresses. We dissected the genetic architecture of heading date (HD) by phenotyping a doubled haploid (DH) population (178 ...
Qiongyao Xiang, Shaoxin Wu, Yanhao Zhao, Fei Lu, Yurong Jiang, Xin Hu, Lei Yang, Junkang Rong   +7 more
doaj   +1 more source

Identification of QTLs for wheat heading time across multiple-environments. [PDF]

Theor Appl Genet, 2022
Benaouda S, Dadshani S, Koua P, Léon J, Ballvora A.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Mapping of QTLs for frost tolerance and heading time using SSR markers in bread wheat [PDF]

, 2011
Selection for complex genetic traits, such as frost tolerance, can be simplified in plant breeding programs when linked markers were detected. The use of microsatellite markers for tagging and mapping important genes or QTLs is a goal in wheat genetic ...
Sofalian, O, Mohammadi, SA, Aharizad, S, Shakiba, MR, Moghaddam, M   +4 more
core   +1 more source

CRISPR/Cas9-induced modification of the conservative promoter region of VRN-A1 alters the heading time of hexaploid bread wheat. [PDF]

Front Plant Sci, 2022
Miroshnichenko D, Timerbaev V, Klementyeva A, Pushin A, Sidorova T, Litvinov D, Nazarova L, Shulga O, Divashuk M, Karlov G, Salina E, Dolgov S.   +11 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Soft control performance (avg. T) for different θ_s, ρ_n and M in the fixed-heading-shill scenario with l = 25.

, 2018
Soft control performance (avg. T) for different θs, ρn and M in the fixed-heading-shill scenario with l = 25.
Caiyun Wang (179623), Jing Han (43038)
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Growth and production characters of elymus cylindricus in different shortening heading time

, 2019
Ramet modules in a certain population differ in terms of functions, which accounts for different contributions of the same ramets. Shortening heading time brings about different contributions of such modules. Ramets heading one after another were treated
Chan Zhou, Chengcheng Li, Yunfei Yang
core   +1 more source

Allelic variations of Vrn-1 and Ppd-1 genes in Japanese wheat varieties reveal the genotype-environment interaction for heading time. [PDF]

Breed Sci, 2022
Mizuno N, Matsunaka H, Yanaka M, Nakata M, Nakamura K, Nakamaru A, Kiribuchi-Otobe C, Ishikawa G, Chono M, Hatta K, Fujita M, Kobayashi F.   +11 more
europepmc   +1 more source