Results 81 to 90 of about 14,560,647 (251)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Expression of Concern: EARLY FLOWERING 3 interactions with PHYTOCHROME B and PHOTOPERIOD1 are critical for the photoperiodic regulation of wheat heading time. [PDF]

PLoS Genet, 2023
PLOS Genetics Editors.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The effects of heading time on yield performance and HvGAMYB expression in spring barley subjected to drought. [PDF]

J Appl Genet, 2023
Ogrodowicz P, Kuczyńska A, Krajewski P, Kempa M.   +3 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pre-Processing Technique for Compass-less Madgwick in Heading Estimation for Industry 4.0

, 2020
The high quality of heading orientation is a key factor to monitor the industrial robot arms in the Industry 4.0. The paper proposes a new algorithm ‘No Motion No Integration’ (NMNI) to enhance the gyroscope performance via signal processing and ...
Vincenzo Paciello, Salvatore Dello Iacono, Antonio Pietrosanto, Minh Long Hoang   +3 more
core  

Predicting the present direction of heading [PDF]

, 1999
Humans perceive heading accurately when they rotate their eyes. This is remarkable, because (1) the pursuit eye movement makes the retinal flow more complicated; and (2) the eye rotation causes a continuous change of the heading direction on the retina ...
van den Berg, A.V, van den Berg, AV (Albert)   +1 more
core   +1 more source

Heading in Female Soccer: A Scoping Systematic Review

Sports
Heading is a key skill in soccer, and it is few investigated in females. Research on heading focused mostly on males and on young players. Data on females’ soccer players are sparse and it is difficult to draw firm conclusions.
Yinhao Shen, Shinting Chen, Qingguang Liu, Antonio Cicchella   +3 more
doaj   +1 more source

EARLY FLOWERING 3 interactions with PHYTOCHROME B and PHOTOPERIOD1 are critical for the photoperiodic regulation of wheat heading time. [PDF]

PLoS Genet, 2023
Alvarez MA, Li C, Lin H, Joe A, Padilla M, Woods DP, Dubcovsky J.   +6 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source