Results 61 to 70 of about 90,704 (330)

Study on the Nonlinear Permeability Mechanism and Pore Structure Characteristics of Deep Confined Aquifers

open access: yesApplied Sciences, 2023
The study of deep soil mechanics is the basis of deep shaft construction. Exploring the nonlinear permeability mechanism of deep confined aquifers in depth is the prerequisite and foundation for carrying out calculations of the hydrophobic consolidation ...
Shilong Peng   +3 more
doaj   +1 more source

Psychophysicl calibration for controlling the range of a virtual sound source: Multidimensional complexity in spatial auditory display [PDF]

open access: yes, 2001
Presented at the 7th International Conference on Auditory Display (ICAD), Espoo, Finland, July 29-August 1, 2001.Presented at the 7th International Conference on Auditory Display (ICAD), Espoo, Finland, July 29-August 1, 2001.Just as control over ...
Martens, William L
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The effect of pitch shifts on the identification of environmental sounds: Design considerations for the modification of sounds in auditory displays [PDF]

open access: yes, 2005
Presented at the 11th International Conference on Auditory Display (ICAD2005)Presented at the 11th International Conference on Auditory Display (ICAD2005)To examine the plausibility of dynamically adjusting the sounds presented by an auditory display, a ...
Brock, Derek   +4 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Heads-Up Three-Dimensional Viewing Systems in Vitreoretinal Surgery: An Updated Perspective

open access: yesClinical Ophthalmology, 2023
Peyman Razavi,1 Bertan Cakir,2 Grace Baldwin,2 Donald J D’Amico,1 John B Miller2 1Department of Ophthalmology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, NY, USA; 2Harvard Retinal Imaging Lab, Boston, MA, USACorrespondence ...
Razavi P   +4 more
doaj  

[Calligraphy Crazy Heads BOH 1193] [PDF]

open access: yes, 2005
Red hair, with purple face. Red/green and blue calligraphy.RVITOEIQIND OLOIXLILOIEEOR PVLVVOINVLOPI ONIOHLYOEOI? EIIALO Omiomytium RODNITLEOF _RAQIAOKElo OLILA"OanOOK ELVAPI__Epotiu {/:VEVRVS{:PTiff file: 2040 x 1539 pixels, 8.98 Mb; Display: jpeg, 600
Catich, Father Edward Catich
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

[Calligraphy Crazy Heads BOH 1195] [PDF]

open access: yes, 2005
Black hair with blue circles around eyes and neck. Calligraphy below along with marble paper.Ariadne [above] Lenska [below]Tiff file: 1998 x 1488 pixels, 8.51 Mb; Display: jpeg, 600 x 447 pixels ...
Father Edward Catich
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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