Results 121 to 130 of about 1,754,133 (312)

Decreased glomerular function is associated with disease severity in patients with hidradenitis suppurativa

open access: yesHealth Science Reports, 2022
Valdemar W. Nielsen   +6 more
doaj   +1 more source

Upper and Lower Limb Muscle Activation during Green Care: An Electromyographic Analysis

open access: yesHortScience
Green care activities are associated with lower intensity and a lower risk of injury than agricultural activities aimed at producing agricultural and livestock products; however, the risk of health problems cannot be completely ruled out.
Seon-Ok Kim   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The role of initial geometry in experimental models of wound closing

open access: yes, 2017
Wound healing assays are commonly used to study how populations of cells, initialised on a two-dimensional surface, act to close an artificial wound space.
Chou, Shih-En   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Modelling strategies for the healing of burn wounds [PDF]

open access: yes, 2007
Epidermal wound healing requires the coordinated involvement of complex cellular and biochemical processes. In the case of epidermal wounds associated with burns, the healing process may be less than optimal and may take a significant amount of time ...
Denman, Paula Kerri
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Human adipose-derived stem cell exosomes reduce mitochondrial DNA common deletion through PINK1/Parkin-mediated mitophagy to improve skin photoaging

open access: yesStem Cell Research & Therapy
Backgroud Mitochondrial DNA (mtDNA) deletion and oxidative stress are key contributors to skin photoaging. Mitophagy helps mitigate oxidative stress.
Yihao Wang   +6 more
doaj   +1 more source

In The Trenches: Traditional Healers\u27 Understanding of Health and Healing [PDF]

open access: yes, 2016
This study explored understandings of traditional healing from the perspectives of traditional healers and helpers. The sample of sixteen individuals was initially identified by key informants, and then the sample snowballed by word of mouth.
Hill, Gus
core   +1 more source

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