Results 141 to 150 of about 1,193,909 (297)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Time-dependent efficacy of seven pharmacological regimens for ulcer healing and delayed bleeding prevention after gastric endoscopic submucosal dissection: A frequentist network meta-analysis. [PDF]

PLoS One
Li L, Zhu X, Hu H.
europepmc   +1 more source

Healing to be Healed - After the Maraş Earthquake

Turkish Journal of Psychiatry, 2023
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Association Between Wound Exudate Severity and Time to Healing Among Patients with Venous Leg Ulcers (VLUs): A Real-World Retrospective Cohort Study. [PDF]

Vasc Health Risk Manag
Gloviczki P, Han Y, Velickovic V, Gahlon G, Santoso C, Corman SL, Armstrong DG, Kottner J, Rothman KJ.   +8 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Association of Wound Exudate Severity on Time to Complete Healing in Diabetic Foot Ulcers: A Real-World Retrospective Cohort Analysis (ExAct DFU Study). [PDF]

Diabetes Metab Syndr Obes
Armstrong DG, Gahlon G, Veličković V, Han Y, Sanaeifar N, Corman SL, Gloviczki P, Kottner J, Rothman KJ.   +8 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Automated Prediction of Diabetes-Related Foot Ulcer Healing at Initial Assessment. [PDF]

J Diabetes Sci Technol
Sari NN, Ngo QC, Ogrin R, Hanna S, Waller K, Polus B, MacIsaac RJ, Ekinci E, Kumar DK.   +8 more
europepmc   +1 more source

The Art of Healing and the Healing of Art

Journal of Cardiac Failure - Intersections
KATZ, JASON N., KATZ, ALANNA R., REZA, NOSHEEN   +2 more
openaire   +3 more sources