Results 91 to 100 of about 1,678,393 (352)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

open access: yesNeuropsychiatric Disease and Treatment, 2012
Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1–3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming ...
Chen YZ   +5 more
doaj  

Mental Health and Health-Related Quality-of-Life Outcomes Among Frontline Health Workers During the Peak of COVID-19 Outbreak in Vietnam: A Cross-Sectional Study

open access: yesRisk Management and Healthcare Policy, 2020
Hung Manh Than,1,* Vuong Minh Nong,2,* Cap Trung Nguyen,1 Khiem Phu Dong,3 Hoa Thi Ngo,4 Tra Thu Doan,2 Nga Thu Do,2 Trang Huyen Thi Nguyen,5 Thanh Van Do,2 Co Xuan Dao,6 Tuan Quang Nguyen,6 Thach Ngoc Pham,3 Cuong Duy Do2 1Emergency Department, National
Manh Than H   +12 more
doaj  

HEALTH-RELATED FAMILY QUALITY OF LIFE WHEN A CHILD OR YOUNG PERSON HAS A DISABILITY

open access: yesInternational Journal of Child, Youth & Family Studies, 2018
Parents of a child or young person with disability face not only the same challenges as parents of typically developing children and young people, but also the extra challenges of supporting the child or young person with disability in such a way as to ...
Margaret R. Kyrkou
doaj   +1 more source

Health-related quality of life after liver transplantation [PDF]

open access: bronze, 1998
A Hellgren   +5 more
openalex   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Health-related quality of life assessment in people with multiple sclerosis and their family caregivers. A multicenter study in Catalonia (Southern Europe)

open access: yesPatient Preference and Adherence, 2009
Marta Aymerich1, Imma Guillamón2, Albert J Jovell3,41Medical Sciences Department, University of Girona, Catalonia, Spain; 2Catalan Agency for Health Technology Assessment and Research, Barcelona, Catalonia, Spain; 3Fundaci&oacute ...
Marta Aymerich   +2 more
doaj  

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2012
Martin Strassnig,1 Jaspreet S Brar,2 Rohan Ganguli31Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL, USA; 2Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Psychiatry, Centre for ...
Strassnig M, Brar JS, Ganguli R
doaj  

ORAL HEALTH-RELATED QUALITY OF LIFE in CHILDREN AND ADOLESCENTS UNDERGOING ORTHODONTIC TREATMENT

open access: yesRomanian Journal of Oral Rehabilitation, 2022
Quality of Life (QoL) has an impact on the interaction and social integration of people, helping with self-confidence and well-being, which may or may not be influenced by the presence of malocclusions.
Alice Chehab   +5 more
doaj  

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