Results 71 to 80 of about 172,642,443 (258)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Systematic review of health-related quality of life models [PDF]

, 2012
A systematic literature review was conducted to (a) identify the most frequently used health-related quality of life (HRQOL) models and (b) critique those ...
McLennon, Susan M., Bakas, Tamilyn, Susan M McLennon, Tamilyn Bakas, Janet S Carpenter, Otte, Julie L., Kathleen M Hanna, Julie L Otte, Kimberly A Hadler, Ellett, Marsha L., Hanna, Kathleen M., Janet L Welch, Buelow, Janice M., Marsha L Ellett, Janice M Buelow, Hadler, Kimberly A., Carpenter, Janet S., Welch, Janet L.   +17 more
core   +1 more source

Lifestyle Habits Determinants of Health-Related Quality of Life in Moroccan College Students

, 2023
The transition to university is a critical period during which considerable life changes arise. Useful national data to design tailored interventions aimed at promoting health-related quality of life (HRQoL) among Moroccan students are lacking.
Abdelghafour Marfak, Chakib Nejjari, Asmaa Azizi, Doha Achak, Elmadani Saad, Ibtissam Youlyouz-Marfak, Abderraouf Hilali, Abdelghaffar El-Ammari   +7 more
core   +1 more source

Irrational parenthood cognitions and health-related quality of life among infertile women

International Journal of General Medicine, 2012
Zahra Fardiazar,1 Louiz Amanati,2 Saber Azami31Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Faculty of Medicine, Hacttepe University, Ankara, Turkey; 3Injury Epidemiology and Prevention ...
Fardiazar Z, Amanati L, Azami S
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The impact of biologics on health-related quality of life in patients with inflammatory bowel disease

Clinical and Experimental Gastroenterology, 2009
Lauran Vogelaar1, Adriaan van’t Spijker2, C Janneke van der Woude11Department of Gastroenterology and Hepatology, 2Department of Psychology and Psychotherapy, Erasmus Medical Centre, RotterdamBackground: Inflammatory bowel disease (IBD) is ...
Lauran Vogelaar, Adriaan van’t Spijker, C Janneke van der Woude   +2 more
doaj  

Mental Health and Health-Related Quality-of-Life Outcomes Among Frontline Health Workers During the Peak of COVID-19 Outbreak in Vietnam: A Cross-Sectional Study

Risk Management and Healthcare Policy, 2020
Hung Manh Than,1,* Vuong Minh Nong,2,* Cap Trung Nguyen,1 Khiem Phu Dong,3 Hoa Thi Ngo,4 Tra Thu Doan,2 Nga Thu Do,2 Trang Huyen Thi Nguyen,5 Thanh Van Do,2 Co Xuan Dao,6 Tuan Quang Nguyen,6 Thach Ngoc Pham,3 Cuong Duy Do2 1Emergency Department, National
Manh Than H, Minh Nong V, Trung Nguyen C, Phu Dong K, Ngo HT, Thu Doan T, Thu Do N, Huyen Thi Nguyen T, Van Do T, Xuan Dao C, Quang Nguyen T, Ngoc Pham T, Duy Do C   +12 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Impact of metabolic comorbidity on the association between body mass index and heatlh-related quality of life: a Scotland-wide cross-sectional study of 5,608 participants [PDF]

, 2012
<p/>Background: The prevalence of obesity is rising in Scotland and globally. Overall, obesity is associated with increased morbidity, mortality and reduced health-related quality of life.
Zia Ul-Haq, Ul-Haq Zia, Elisabeth Fenwick, Ul-Haq, Z., Mackay, D., Fenwick Elisabeth, Pell, J., Mackay Daniel F, Fenwick, E., Jill P Pell, Daniel F Mackay, Pell Jill P   +11 more
core   +2 more sources