Results 61 to 70 of about 1,648,841 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The impact of biologics on health-related quality of life in patients with inflammatory bowel disease

Clinical and Experimental Gastroenterology, 2009
Lauran Vogelaar1, Adriaan van’t Spijker2, C Janneke van der Woude11Department of Gastroenterology and Hepatology, 2Department of Psychology and Psychotherapy, Erasmus Medical Centre, RotterdamBackground: Inflammatory bowel disease (IBD) is ...
Lauran Vogelaar, Adriaan van’t Spijker, C Janneke van der Woude   +2 more
doaj  

Mental Health and Health-Related Quality-of-Life Outcomes Among Frontline Health Workers During the Peak of COVID-19 Outbreak in Vietnam: A Cross-Sectional Study

Risk Management and Healthcare Policy, 2020
Hung Manh Than,1,* Vuong Minh Nong,2,* Cap Trung Nguyen,1 Khiem Phu Dong,3 Hoa Thi Ngo,4 Tra Thu Doan,2 Nga Thu Do,2 Trang Huyen Thi Nguyen,5 Thanh Van Do,2 Co Xuan Dao,6 Tuan Quang Nguyen,6 Thach Ngoc Pham,3 Cuong Duy Do2 1Emergency Department, National
Manh Than H, Minh Nong V, Trung Nguyen C, Phu Dong K, Ngo HT, Thu Doan T, Thu Do N, Huyen Thi Nguyen T, Van Do T, Xuan Dao C, Quang Nguyen T, Ngoc Pham T, Duy Do C   +12 more
doaj  

Health‐related quality of life of children with strabismus

Acta Ophthalmologica
Abstract Purpose The agreement between children with strabismus and their parents on the health‐related quality of life (HRQOL) of the child is unknown. Additionally, it is unknown if physical traits pre‐dispose to a better outcome in HRQOL after strabismus surgery in children.
Lena Boulakh, Jonas L. Isaksen, Christina Ellervik, Jørgen K. Kanters, Helena Buch Hesgaard, Lisbeth Sandfeldt   +5 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The association of drooling and health-related quality of life in children with cerebral palsy

Neuropsychiatric Disease and Treatment, 2012
Shih-Chung Chang,1 Chin-Kai Lin,2 Li-Chen Tung,3 Nai-Yin Chang11Department of Physical Medicine and Rehabilitation, School of Medicine, Chung Shang Medical University Hospital, Taichung, Taiwan; 2Program of Early Intervention, Department of Early ...
Chang SC, Lin CK, Tung LC, Chang NY
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Health-related quality of life assessment in people with multiple sclerosis and their family caregivers. A multicenter study in Catalonia (Southern Europe)

Patient Preference and Adherence, 2009
Marta Aymerich1, Imma Guillamón2, Albert J Jovell3,41Medical Sciences Department, University of Girona, Catalonia, Spain; 2Catalan Agency for Health Technology Assessment and Research, Barcelona, Catalonia, Spain; 3Fundaci&oacute ...
Marta Aymerich, Imma Guillamón, Albert J Jovell   +2 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Health-related quality of life, adiposity, and sedentary behavior in patients with early schizophrenia: preliminary study

Diabetes, Metabolic Syndrome and Obesity, 2012
Martin Strassnig,1 Jaspreet S Brar,2 Rohan Ganguli31Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL, USA; 2Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 3Department of Psychiatry, Centre for ...
Strassnig M, Brar JS, Ganguli R
doaj