Results 91 to 100 of about 172,642,443 (258)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The unfolding method to explore health-related quality of life constructs in a Chinese general population [PDF]
, 2021 Objectives: Health-related quality of life (HRQOL) is a complicated concept that can be measured using multiple health items. Although HRQOL is closely associated with people's subjective assessment of their own health, a limited number of studies have ...
Graham, Christopher +3 more
core
Patient Preference and Adherence, 2020 Binh Thang Tran,1,2 Nhu Hiep Pham,3 Thanh Xuan Nguyen,3 Kui Son Choi,1,4 Dae Kyung Sohn,1,5 Sun-Young Kim,1 Jae Kyung Suh,6 Thuy Duyen Nguyen,1,7 Van Sang Phan,2 Dinh Trung Tran,8 The Thanh Nguyen,9 Thi Thanh Binh Nguyen,10 Minh Tu Nguyen,11 Jin-Kyoung ...
Tran BT +13 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Institutionalisation and Quality of Life for Elderly People in Finland. ENEPRI Research Report No. 92, August 2011 [PDF]
, 2011 In this paper we examine whether there are systematic differences between the quality of life of an individual who is institutionalised and one who is not, keeping health status and income level constant.
Johansson, Edvard. +2 more
core
International Journal of COPD, 2014 Amy Blakemore,1,2 Chris Dickens,3 Else Guthrie,2 Peter Bower,1 Evangelos Kontopantelis,1 Cara Afzal,2 Peter A Coventry4 1National Institute for Health Research School for Primary Care Research, Centre for Primary Care, Manchester Academic Health Science ...
Blakemore A +6 more
doaj
Indian Journal of Public HealthBackground: Children’s health-related quality of life (HRQoL) varies in their country’s conditions, with physical and mental well-being challenges being more prevalent in low- and middle-income countries.
Sadia Alam Aivey +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Health-related quality of life in epilepsy: findings obtained wiht a new italian instrument.
, 2008 The aim of the present study was to evaluate the Epi-QoL, a new Italian-specific measure of health-related quality of life (HRQOL) for adults with epilepsy; the clinical variables that affected the HRQOL score were also assessed.
K. Turner +5 more
core +1 more source
Journal of Pediatric Critical CareBackground: The pediatric intensive care unit (PICU) has reduced mortality, but survival alone does not reflect long-term outcomes. Health-related quality of life (HRQoL) is a key measure of recovery, with limited data in PICU survivors, especially in ...
Siva Vyasam +4 more
doaj +1 more source