Results 111 to 120 of about 4,421,151 (391)

The longitudinal relationships between pain severity and disability versus health-related quality of life and costs among chronic low back pain patients

open access: yesQuality of Life Research, 2019
Purpose Previous studies found higher levels of pain severity and disability to be associated with higher costs and lower health-related quality of life.
Elizabeth N. Mutubuki   +9 more
semanticscholar   +1 more source

Ear- and hearing-related impact on quality of life in children with cleft palate : development and pretest of a health-related quality of life (HRQOL) instrument

open access: yes, 2019
Objectives: To investigate to what extent middle ear problems and associated hearing loss affect quality of life (QoL) of children born with a cleft palate. Methods: Fifty-five children aged between 6 and 18 years, born with non-syndromic cleft palate +/
De Leenheer, Els   +4 more
core   +2 more sources

Maltese children with a hearing impairment : analysis of the current situation and its impact on the quality of life of parents [PDF]

open access: yes, 2015
Understanding the effect that a diagnosis of a childhood hearing loss has on parents would help professionals adopt an approach which diminishes parents’ possible negative feelings and concerns. A sample of parents of children with hearing impairment
Grima, Ritienne, Sciberras, Stefan
core   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Irrational parenthood cognitions and health-related quality of life among infertile women

open access: yesInternational Journal of General Medicine, 2012
Zahra Fardiazar,1 Louiz Amanati,2 Saber Azami31Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; 2Faculty of Medicine, Hacttepe University, Ankara, Turkey; 3Injury Epidemiology and Prevention ...
Fardiazar Z, Amanati L, Azami S
doaj  

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Asthma and Health-Related Quality of Life

open access: yesAllergology International, 2005
ABSTRACTThe health-related quality of life (HRQoL) is assessed using instruments that have been validated scientifically. From the viewpoint of assessment, they are different from other clinical indices because the subjects themselves evaluate their own HRQoL (the patients in many clinical settings).
openaire   +3 more sources

The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review [PDF]

open access: yes, 2004
Background The goal of much care in chronic childhood illness is to improve quality of life (QOL). However, surveys suggest QOL measures are not routinely included.
Clarke, S., Eiser, C.
core   +3 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

The impact of biologics on health-related quality of life in patients with inflammatory bowel disease

open access: yesClinical and Experimental Gastroenterology, 2009
Lauran Vogelaar1, Adriaan van’t Spijker2, C Janneke van der Woude11Department of Gastroenterology and Hepatology, 2Department of Psychology and Psychotherapy, Erasmus Medical Centre, RotterdamBackground: Inflammatory bowel disease (IBD) is ...
Lauran Vogelaar   +2 more
doaj  

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