Results 171 to 180 of about 29,484,777 (402)

Institutions Accredited by the American Public Health Association to Give the Degree of Doctor of Public Health for the Academic Year 1946-1947

open access: green, 1946
William P. Shepard   +12 more
openalex   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Ambient air pollution: a global assessment of exposure and burden of disease

open access: yesClean Air Journal, 2016
World Health Organization
doaj   +1 more source

Book: Küme mongen en el lof Temulemu. Diagnóstico de salud. Conclusiones y propuestas, 2023

open access: yesSocial Medicine
The diagnosis of lof Temulemu aims to provide an overview of the situation of the Küme mongen, good life or well-being from the perspective of the Mapuche families that comprise it. It is mainly based on the analysis of the results of the survey applied
PRI Lonco Comprehensive Indigenous Health Plan - Lof Temulemu and Araucanía North Health Service, Ministry of Health, Government of Chile
doaj  

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