Results 131 to 140 of about 5,610 (315)

The intervention of social leisure on the loneliness, attachment, and wellbeing relationship among older adults: Resilience amid COVID-19 pandemic [PDF]

open access: yes
Dr. Jessie Gao is a Research Scientist for the Canadian Index of Wellbeing. She is in charge of updating and maintaining the CIW's data repository, preparing various CIW wellbeing reports and publishing academic articles.
Gao, Mingjie Jessie, Smale, Bryan
core  

Community led housing, health and wellbeing: a comprehensive literature review [PDF]

open access: yes
Community Led Housing (CLH) is an umbrella term encompassing several non-profit models of housing delivery, which is used internationally. There has been little comprehensive assessment of the health impacts of housing arrangements where people ...
McClatchey, Rachael   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Victorian population health survey 2012 [PDF]

open access: yes, 2016
Collects information at the State, regional and local government area levels about the health, lifestyle and wellbeing of adult Victorians aged 18 years and over.
Department of Health (Victoria)
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

International Digital Mental Health & Wellbeing Conference 2025 [PDF]

open access: yes
Mental ill health is prevalent, and citizens need more support to prevent mental ill health as well as supporting their treatment and management of their mental health and wellbeing.
McAllister, Patrick, Gorman, Colin
core   +1 more source

Grand challenge: addressing the global challenge of healthy aging

open access: yesFrontiers in Public Health
This article reflects upon contemporary issues for the study of healthy ageing and highlights several grand challenges for public health and ageing.
Colette Browning   +6 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Prevention of postpartum depression via a digital acceptance and commitment therapy-based intervention: protocol for a pilot usability study

open access: yesFrontiers in Psychiatry
IntroductionThe perinatal period — encompassing pregnancy and the first months after childbirth — is a time of increased psychological vulnerability. It is often associated with high levels of anxiety, stress and depression.
Silvia Rizzi   +15 more
doaj   +1 more source

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