Results 141 to 150 of about 5,610 (315)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Eco-affective health: a framework and testable hypotheses for the affective dimensions of human-nature disconnection and reconnection in conservation science

Frontiers in Conservation Science
Conservation science has made extraordinary progress in documenting the ecological systems we are losing. It has made far less progress in understanding the human affective systems that determine whether those ecological systems will be protected ...
Lucas Murrins Marques, Lucas Murrins Marques   +1 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Impact of mental health on youths' overall wellbeing and positive outlook [PDF]

This article reports on the overall wellbeing and positive outlook of 106 pupils in a city secondary school in England. The pupils were in Year 7 (n=38) [age 11-12], Year 8 (n=31) [age 12-13], and Year 10 (n=37) [age 14-15].
Pilkington, Tim, Glazzard, Jonathan, Fenwick, Ben, Dockerty, Kelly   +3 more
core   +1 more source

The Case for Change & An Ethical Approach to Wellbeing Management in Aviation: Wellbeing II and Advancing an Integrated Health & Safety Culture

, 2021
PUBLISHED
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Choral singing and psychological wellbeing [PDF]

, 2009
  Over 600 choral singers drawn from English choirs completed the WHOQOL-BREF questionnaire to measure physical, psychological, social and environmental wellbeing, and a twelve-item ‘wellbeing and choral singing scale’.
Don Stewart, Stephen Clift, Barbel Hess, Gunter Kreutz, Grenville Hancox, Ian Morrison   +5 more
core  

Made in China: The international supply of illicit Semaglutide and weight-loss medicines online

Emerging Trends in Drugs, Addictions, and Health
Background: The use of GLP-1 medicines for weight-loss purposes is increasingly widespread. While these drugs are available as prescription medicines in the UK, there is an expansive illicit market for their supply operating online.
Luke A. Turnock, Evelyn Hearne, Lambros Lazuras   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source