Results 201 to 210 of about 1,752,033 (265)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Expanding the definition of unmet medical need: Findings from a multistakeholder workshop. [PDF]

open access: yesJ Manag Care Spec Pharm
Zemplenyi A   +4 more
europepmc   +1 more source

A pilot study of at-home online cognitive screening prior to primary care wellness visits for older adults. [PDF]

open access: yesFront Digit Health
Thompson L   +15 more
europepmc   +1 more source

Changes in physical performance and frailty-associated risk associated with participation in a community exercise programme: Findings from the ExWell cohort. [PDF]

open access: yesJ Frailty Aging
O'Shea M   +8 more
europepmc   +1 more source

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