Results 51 to 60 of about 1,023,066 (309)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Physical exercise moderates the mediating effect of depressive symptoms between sleep quality and suicidal ideation among college students

Scientific Reports
Sleep quality is critical for suicidality or psychological well-being in any cohort. However, the underlying psychological and behavioral mechanisms linking these factors remain insufficiently understood.
Yanying Liu, Yao Tong, Guihua Huang, Kelei Guo   +3 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Comparative effectiveness of morning and evening aerobic exercise on weight loss and physical fitness in Chinese college students with overweight and obesity

BMC Sports Science, Medicine and Rehabilitation
Background Physiological and metabolic processes are influenced by biological rhythms. However, whether exercising in the morning or evening is more beneficial, given that these periods are two key time windows to incorporate exercise, has remained ...
Jingyu Sun, Nannan Jia, Yaning Xu, Dakai Guo, Tianfeng Lu, Jiajia Chen, Hang Chu, Zhangxiaohe Zhang, Ke Yao, Rongji Zhao, Tao Chen   +10 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Tropical oils consumption and health: a scoping review to inform the development of guidelines in tropical regions

BMC Public Health
Background Tropical oils such as palm and coconut oils are renowned for their high saturated fat content and culinary versatility. However, their consumption has sparked debate regarding their health benefits and production concerns.
Thomas Hormenu, Iddrisu Salifu, Juliet Elikem Paku, Peace Yaa Kordowu, Adams Abdul-Karim, Thomas Boateng Gyan, Immanuel Asiedu, Osman Abdul-Ganiyu, Mustapha Amoadu   +8 more
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

The mediating role of rumination and psychological resilience between physical activity and sleep quality among college students

Scientific Reports
Sleep quality is a critical issue among college students, significantly affecting their academic performance, mental health, and overall well-being. Identifying the factors affecting sleep quality is crucial for designing effective interventions.
Yanying Liu, Yao Tong, Guihua Huang, Kelei Guo   +3 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

The association between adverse childhood experiences and co-occurrence of health risk behaviors in adolescents: the chained mediating role of self-efficacy and self-control

BMC Psychology
Background The Co-occurrence of Health Risk Behaviors (ACEs) among adolescents has become a significant public health issue that urgently needs to be addressed. This study aims to investigate the prevalence of Co-occurrence of Health Risk Behaviors among
Tao Xu, Yongsheng Wang, Zhengying Han, Lvhao Liu, Jiajia Chen   +4 more
doaj   +1 more source