Results 101 to 110 of about 17,191,357 (315)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Multilevel Analysis on Factors Affecting Caries Preventive Behavior among Primary School Children: Application of Health Belief Model [PDF]

, 2019
Background: Dental caries (tooth decay) is a problem of children’s dental health in the world. Primary school age is a strategic group for the precaution of dental and oral diseases.
Ratih, Dewi Mustika, Dewi, Yulia Lanti Retno, Murti, Bhisma   +2 more
core  

The Relationship of the Health Belief Model to the Prevention Behavior of Metabolic Syndrome: A Meta-Analysis Study [PDF]

, 2022
Background: Risk factors for Metabolic Syndrome include hypertension, glucose intolerance, central obesity and dyslipidemia. These conditions if they occur together are referred to as Metabolic Syndrome which can increase the risk of non-communicable ...
Solehaini, Dena Tri, Mulianda, Cendekia Airedeta   +1 more
core  

Imprecise health beliefs and health behavior

Journal of Health Economics
This paper examines belief imprecision in the context of COVID-19, when uncertainty about health outcomes was widespread. We survey a sample of young adults a few months after the onset of the pandemic. We elicit individuals' minimum and maximum subjective probabilities of different health outcomes, and define belief imprecision as the range between ...
Delavande, Adeline, Del Bono, Emilia, Holford, Angus   +2 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Why do children engage in sedentary behavior? Child- and parent-perceived determinants

, 2017
Todays children spend a large amount of their time sedentary. There is limited evidence on the determinants of sedentary behavior in children, and qualitative studies are especially lacking. Therefore, this study aimed to explore determinants of children’
Altenburg, Teatske M., van Ekris, Evi, Evi Van Ekris, Hidding, Lisan M., Lisan Hidding, Mai Chinapaw, Teatske Altenburg, Chinapaw, Mai J.M.   +7 more
core   +1 more source

Determinants of Premarital Sex Behavior: Application of Theory of Planned Behavior and Social Cognitive Theory [PDF]

, 2021
Background: Health problems in adolescents are among the most important problems in the human life cycle, especially reproductive and sexual problems.
Budihastuti, Uki Retno, Qomariah, Nur Laili, Pamungkasari, Eti Poncorini   +2 more
core  

Factors Associated with Non-Adherence to Blood Glucose Testing Among Non-Hispanic Black and Hispanic Men with a History of Prediabetes in the United States

Patient Preference and Adherence
Aaheli Bose,1 Tyler Prochnow,1– 3 Caroline D Bergeron,4 Jeong-Hui Park,5 Bobbie L Johannes,6 Ledric D Sherman,1,2 Megan S Patterson,1 Ashley L Merianos,7 Matthew Lee Smith8,9 1Department of Health Behavior, School of Public Health, Texas A&M ...
Bose A, Prochnow T, Bergeron CD, Park JH, Johannes BL, Sherman LD, Patterson MS, Merianos AL, Smith ML   +8 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source