Results 111 to 120 of about 2,256,642 (315)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Why do children engage in sedentary behavior? Child- and parent-perceived determinants

, 2017
Todays children spend a large amount of their time sedentary. There is limited evidence on the determinants of sedentary behavior in children, and qualitative studies are especially lacking. Therefore, this study aimed to explore determinants of children’
Altenburg, Teatske M., van Ekris, Evi, Evi Van Ekris, Hidding, Lisan M., Lisan Hidding, Mai Chinapaw, Teatske Altenburg, Chinapaw, Mai J.M.   +7 more
core   +1 more source

Correction to: Bridging the evidence-to-practice gap: a stepped-wedge cluster randomized controlled trial evaluating practice facilitation as a strategy to accelerate translation of a multi-level adherence intervention into safety net practices

Implementation Science Communications, 2021
Antoinette Schoenthaler, Franzenith De La Calle, Amanda Soto, Derrel Barrett, Jocelyn Cruz, Leydi Payano, Marina Rosado, Samrachana Adhikari, Gbenga Ogedegbe, Milagros Rosal   +9 more
doaj   +1 more source

Perception of Social Support and its Relationship With the Biological Rhythm of Women in the Postpartum Period

Interpersona: An International Journal on Personal Relationships
It is known that social support is one of the main protective factors in the postpartum period. In addition, studies report the association between biological rhythm disruption and its consequences on health, especially mental, but little is known about ...
Maria Eduarda Oxley, Bárbara Borges Rubin, Carolina Coelho Scholl, Fernanda Teixeira Coelho, Bruna Beatriz Alves dos Santos, Mariana Bonati de Matos, Gabriele Ghisleni, Karen Amaral Tavares Pinheiro, Luciana de Avila Quevedo, Ricardo Tavares Pinheiro, Jéssica Puchalski Trettim   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Meta-Analysis: Application of Health Belief Model in Encouraging Preventive Behavior of Self-Care for Hypertensive Patients

, 2022
Background: Hypertension is one of the most critical public health problems and has affected more than 1.2 billion people worldwide. Risk factors for hypertension can be divided into two, namely factors that cannot be controlled (such as gender, genetics
Salsabil, Husna Arwa, Firmansyah, Gusti Fathoni   +1 more
core  

[Health and health-related behaviors according to sexual attraction and behavior].

Gaceta sanitaria, 2015
to Describe perceived health, mental health and certain health-related behaviors according to sexual attraction and behavior in the population residing in Barcelona in 2011.Perceived health, mental health, chronic conditions and health-related behaviors were analyzed in 2675 people aged 15 to 64 years.
Perez, G, Marti-Pastor, M, Gotsens, M, Bartoll, X, Diez, E, Borrell, C   +5 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source