Results 91 to 100 of about 2,009,670 (297)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Exploring post-discharge connection for HIV-infected patients in residential centers: perspectives from experts and patients [PDF]

فصلنامه ابن سینا
Background and aims: Many clients referred to accommodation centers and camps are already undergoing antiretroviral treatment after being diagnosed with HIV. Discontinuation or irregular use of medication can lead to treatment failure and drug resistance.
Abbas Boosiraz, Sepideh Alizadeh, Tayebeh Amiri, Zohreh Rostam Afshar, Maryam Sargolzayi Moghadam, Shahrzad Ghorbani, Nazanin Shahrokhnia, Sarina Borran, SeyedAhmad SeyedAlinaghi   +8 more
doaj  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Level and factors of support for the Living with the Virus policy in a Chinese adult general population: a mediation analysis via positive and negative attitudes toward the policy

Frontiers in Public Health
BackgroundThis study investigated the public’s support for the Living with the Virus (LWV) policy, its associated factors, and related mediations at a time when more countries were considering adopting the LWV policy amid the COVID-19 pandemic.MethodsA ...
Joseph T. F. Lau, Joseph T. F. Lau, Joseph T. F. Lau, Joyce Hoi-Yuk Ng, Robin Goodwin, Tarandeep S. Kang, Vivian W. I. Fong, Mason M. C. Lau, Yanqiu Yu   +8 more
doaj   +1 more source

Minority Adolescents at Risk for Obesity: Health Behaviors and Perceptions [PDF]

, 2006
The purpose of this study was to examine behaviors related to nutrition and physical activity of inner-city minority adolescents, and their perception of normal weight and overweight.
Jones, Linda D.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Prevalence and type-specific distribution of human papillomavirus infection among women in mid-western rural, Nepal- A population-based study

BMC Infectious Diseases, 2018
Background Cervical cancer is the most common cancer among women in Nepal. The prevalence of human papillomavirus (HPV) 16 and or HPV 18 among women with cervical pre-cancer and cancer is higher than the incidence of HPV in the world population.
Niresh Thapa, Muna Maharjan, Girishma Shrestha, Narayani Maharjan, Marcia A. Petrini, Na Zuo, Can He, Jing Yang, Mengfei Xu, Caiyun Ge, Ziye Song, Hongbing Cai   +11 more
doaj   +1 more source

Medi-Cal Versus Employer-Based Coverage: Comparing Access to Care [PDF]

, 2015
This report takes a close look at access to care under Medi-Cal for nonelderly adults and children on the eve of Affordable Care Act (ACA) implementation. Using data from the 2012 and 2013 California Health Interview Surveys (CHIS), the research examines
A. J. Scheitler, Ninez A. Ponce, Shana Alex Charles, Tara Becker   +3 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source