Results 101 to 110 of about 2,009,670 (297)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Ethnic inequalities in physico-chemical, physical and social neighborhood exposures: An individual-level data analysis of 13,926,781 adults

open access: yesEnvironment International
Introduction: Ethnic minority populations may be disproportionally affected by unhealthy environmental exposures, increasing health inequities. This study aims to identify whether residential neighborhood exposures differ between ethnic groups in the ...
Mirthe Muilwijk   +7 more
doaj   +1 more source

Behavioral Health [PDF]

open access: yesPhysician Assistant Clinics, 2021
Kim Zuber, Jane S. Davis
openaire   +1 more source

New England Regional Health Equity Profile & Call to Action [PDF]

open access: yes, 2016
Good health is a foundation that allows people to participate in the most important aspects of life. The purpose of the New England Regional Health Equity Profile and Call to Action is to identify where differences in good health exist among racial ...
Chiu, K.   +3 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Stigma and Dissatisfaction of Health Care Personnel in HIV Response in Iran: A Qualitative Study

open access: yesJournal of the International Association of Providers of AIDS Care, 2019
Background and Aims: With regard to the disease pandemics of HIV/AIDS, it is clear that there is need for prevention, treatment, care, and support of HIV positive patients in the health care system.
Mehrnaz Rasoolinejad MD   +6 more
doaj   +1 more source

Influence of Media on Overweight and Obesity Among Latino Youth [PDF]

open access: yes, 2011
Outlines findings about how media marketing affects the health-related behaviors of Latino youth, including trends in television viewing, fast-food advertisement in low-income Latino communities, and snacking and caloric intake.
Amelie Ramirez   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Changes in the Welfare Caseload and the Health of Low-educated Mothers [PDF]

open access: yes
Declines in the welfare caseload in the late 1990s brought significant change to the lives of many low-educated, single mothers. Many single mothers left welfare and entered the labor market and others re-arranged their lives in order to avoid going on ...
Elizabeth Tarlov, Robert Kaestner
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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