Results 61 to 70 of about 272,521 (265)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Linking behaviour change techniques to mechanisms of action: Using the Theory and Techniques Tool alongside the Behaviour Change Intervention Ontology [version 2; peer review: 2 approved]

Wellcome Open Research
Background Understanding how interventions work requires clear hypotheses, rigorous testing, and accurate reporting of links between behaviour change techniques (BCTs)—the smallest replicable active components of interventions—and mechanisms of action ...
Robert West, Micaela Santilli, Paulina M. Schenk, Lisa Zhang, Alison J Wright, Marta M. Marques, Susan Michie, Marie Johnston   +7 more
doaj   +1 more source

Health teaching and behavioural change [PDF]

, 2019
Abstract This chapter discusses health information and raising health awareness. It explains how these feed into behavioural change, both in individuals and in communities, as a key to improving health. It describes ways in which behavioural change can be brought about, starting with transformation in our own attitudes.
openaire   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

An ontological framework for organising and describing behaviours: The Human Behaviour Ontology [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Human behaviours have been classified in domains such as health, occupation and sustainability. We aimed to develop a broadly applicable behavioural framework to facilitate integrating evidence across domains.
Alison J. Wright, Robert West, Janna Hastings, Lisa Zhang, Oscar Castro, Marta M. Marques, Emily Hayes, Elizabeth Corker, Micaela Santilli, Susan Michie, Marie Johnston, Gabriella Stuart, Paulina M. Schenk   +12 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

An ontology of mechanisms of action in behaviour change interventions [version 2; peer review: 2 approved]

Wellcome Open Research
Background Behaviour change interventions influence behaviour through causal processes called “mechanisms of action” (MoAs). Reports of such interventions and their evaluations often use inconsistent or ambiguous terminology, creating problems for ...
Candice Moore, Alison J. Wright, Verena Schneider, Robert West, Emily Hayes, Janna Hastings, Ella Howes, Susan Michie, Fabiana Lorencatto, Paulina M. Schenk   +9 more
doaj   +1 more source

The Human Behaviour-Change Project: harnessing the power of artificial intelligence and machine learning for evidence synthesis and interpretation

Implementation Science, 2017
Background Behaviour change is key to addressing both the challenges facing human health and wellbeing and to promoting the uptake of research findings in health policy and practice.
Susan Michie, James Thomas, Marie Johnston, Pol Mac Aonghusa, John Shawe-Taylor, Michael P. Kelly, Léa A. Deleris, Ailbhe N. Finnerty, Marta M. Marques, Emma Norris, Alison O’Mara-Eves, Robert West   +11 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source