Results 91 to 100 of about 1,127,966 (348)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Factors Related to Nosocomial Infection Control Behaviors in Nurses Working in Hospitals in Jahrom, Iran Based on the Health Belief Model: A Cross-sectional Study

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022
Background and Objectives: Nosocomial infections have always been one of the major health problems, accounting for about one third of all deaths in hospitals. Non-observance of behaviors for their control by nurses is a health behavioral problem.
Rahim Raoufi   +4 more
doaj  

Analysis of Cervical Cancer Preventive Behavior Based on the Health Belief Model [PDF]

open access: yes, 2016
目的: 通过对厦门市学龄期女生母亲宫颈癌预防行为的调查研究,了解女生母亲对 HPV、HPV疫苗、宫颈癌筛查的认知、态度和行为及相关的健康信念;分析女性 对HPV疫苗和宫颈癌筛查的认知、态度和行为的影响因素;以健康信念模式为 理论基础,分析其各部分对宫颈癌预防行为的解释和预测作用,为今后HPV疫 苗的推广和筛查的普及提供基础数据和政策建议。 方法: 本研究以厦门市学龄期女生母亲为研究对象,采用多阶段随机抽样的方法, 对抽取的调查对象采取自填式问卷调查。用相对数描述调查对象的社会人口学特 ...
张钰颖
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Vaccination Hesitation: Investigation Why Parents Decline Pediatric Influenza Vaccines in Juneau, Alaska [PDF]

open access: yes, 2015
The influenza virus is responsible for hundreds of childhood deaths and costs the health care system millions of dollars each year (Hassan, Lewis, Davis, Gebremariam, and Dombkowski, 2009).
Leder, Lindsey
core  

Migrant Farmworkers\u27 Perceptions of Pesticide Risk Exposure in Adams County, Pennsylvania: A Cultural Risk Assessment [PDF]

open access: yes, 2018
Agricultural exceptionalism, a system in which regular labor laws and standards do not apply to farm labor, makes migrant farmworkers particularly vulnerable populations—economically, socially, and in terms of environmental health.
Edelson, Micaela S. G.   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Effect of A Health Belief Model ( HBM)- based Educational Program on the Nutritional Behavior of Menopausal Women in Isfahan [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2011
Introduction :Menopausal women are at risk of chronic diseases due to estrogen deficiency.One of the most effective ways for prevention and control of chronic diseases in menopausal women is changing their nutritional behavior.
Soheila Davari   +4 more
doaj  

FAKTOR KEBERLANJUTAN PENGGUNAAN IUD BERDASARKAN TEORI HEALTH BELIEF MODEL

open access: yesPediomaternal Nursing Journal, 2014
Recently IUD is widely use for long-term contraception method but the usage tendency decrease the number of year. IUD discontinuations rise up. So far, factors related to IUD continuation had not been explained.
Purwoning Husnul C   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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