Results 61 to 70 of about 156,647 (258)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Background: Iron deficiency is one of the most important cause of anemia, the aim of this study was designed to investigate the effect of health education based on HBM model on knowledge, attitude and practice of Gorgan guidance school students about ...
Morteza .Mansourian +7 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Predictors of smoking among the secondary high school boy students based on the health belief model
Background: Smoking is one of the most important risk factors for health and also health problems, such as heart diseases, especially for young people.
Samira Mohammadi +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The Effect of A Health Belief Model ( HBM)- based Educational Program on the Nutritional Behavior of Menopausal Women in Isfahan [PDF]
Introduction :Menopausal women are at risk of chronic diseases due to estrogen deficiency.One of the most effective ways for prevention and control of chronic diseases in menopausal women is changing their nutritional behavior.
Soheila Davari +4 more
doaj
Background and Objectives: Nosocomial infections have always been one of the major health problems, accounting for about one third of all deaths in hospitals. Non-observance of behaviors for their control by nurses is a health behavioral problem.
Rahim Raoufi +4 more
doaj

