Results 71 to 80 of about 1,669,382 (263)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lipid Profiling of Four Guava Cultivars: A Multi-Dimensional Spatial Analysis

open access: yesFoods
This study aimed to reveal the lipid composition and distribution and characterize the lipid metabolism profile in the three distinct parts of four guava varieties with varying textures and colors using liquid chromatography–electrospray ionization ...
Qun Zhang   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Atomic Bomb Health Benefits

open access: yesDose-Response, 2008
“The collected data strongly suggest that low-level radiation is not harmful, and is, in fact, frequently ‘apparently beneficial’ for human health.” — Kondo, 1993 Media reports of deaths and devastation produced by atomic bombs convinced people around ...
T. D. Luckey
doaj   +1 more source

Employee Health Benefit Programs [PDF]

open access: yesPublic Health Reports (1896-1970), 1957
Two major developments in recent years have had a significant effect on the health status of millions of American workers. One has been the shifting emphasis of inplant health programs from care of work injuries to concern for the general health of the worker.
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Viewpoint: Religion benefits health [PDF]

open access: yesBritish Journal of General Practice, 2014
In November 2011, I finally gave in to my bowels. Frequency and slime were one thing, but bleeding was the game changer. A delay of 6 months cost me a lymph node, allowing my rectum to enjoy a second course of chemotherapy. The offending mass had already been removed and fried and a year later, cancer over and my white count recovering, I was back at ...
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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