Results 81 to 90 of about 1,582,189 (264)
Improving the health benefits of wheat
Czech Journal of Genetics and Plant Breeding, 2011 Analysis of wheat lines in the HEALTHGRAIN diversity screen has shown wide variation in the content of phytochemicals, dietary fibre components and minerals.
P. R. SHEWRY +6 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Dose-Response, 2008 “The collected data strongly suggest that low-level radiation is not harmful, and is, in fact, frequently ‘apparently beneficial’ for human health.” — Kondo, 1993 Media reports of deaths and devastation produced by atomic bombs convinced people around ...
T. D. Luckey
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Biopolymers for Enhanced Health Benefits
International Journal of Molecular Sciences, 2023 The definition of the term biopolymer is often controversial, and there is no clear distinction between “biopolymers”, “bioplastics”, and “bio-based polymers” [...]
openaire +2 more sources
Lipid Profiling of Four Guava Cultivars: A Multi-Dimensional Spatial Analysis
FoodsThis study aimed to reveal the lipid composition and distribution and characterize the lipid metabolism profile in the three distinct parts of four guava varieties with varying textures and colors using liquid chromatography–electrospray ionization ...
Qun Zhang +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Health benefits of volunteering
, 2011 The proposal seems too good to be true: give time to help others, and benefit yourself too. Be healthier and eventually live longer. Would it be so simple? Studies actually suggest there may be some truth in the idea that helping others through volunteer work helps people stay healthy. Yet many of these studies use small samples.
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source