Results 101 to 110 of about 8,126,628 (341)

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

open access: yesMolecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen   +6 more
wiley   +1 more source

Integrated Care to Address the Physical Health Needs of People with Severe Mental Illness : A Mapping Review of the Recent Evidence on Barriers, Facilitators and Evaluations [PDF]

open access: yes, 2018
People with mental health conditions have a lower life expectancy and poorer physical health outcomes than the general population. Evidence suggests this is due to a combination of clinical risk factors, socioeconomic factors, and health system factors ...
Department of Health   +17 more
core   +4 more sources

Strengthening of primary health care: Key to deliver inclusive health care

open access: yesIndian Journal of Public Health, 2013
Inequity and poverty are the root causes of ill health. Access to quality health services on an affordable and equitable basis in many parts of the country remains an unfulfilled aspiration. Disparity in health care is interpreted as compromise in ′Right
Rajiv Yeravdekar   +4 more
doaj   +1 more source

Designing Technologies for Value-based Mental Healthcare: Centering Clinicians' Perspectives on Outcomes Data Specification, Collection, and Use [PDF]

open access: yes
Health information technologies are transforming how mental healthcare is paid for through value-based care programs, which tie payment to data quantifying care outcomes. But, it is unclear what outcomes data these technologies should store, how to engage users in data collection, and how outcomes data can improve care.
arxiv   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Perspectives Volume 6: Number 1, Winter-Spring 2018 [PDF]

open access: yes, 2018
https://nsuworks.nova.edu/hpd_hcs_magazine/1010/thumbnail ...
College of Health Care Sciences
core   +1 more source

Primary care provision for mental health

open access: yesNew Zealand Medical Student Journal, 2020
The treatment of mental illness in New Zealand has seen a steady transition from institutionalised to community-based care, from the mental institutions of the late 19th century to the service-based facilities we see today.
Samantha Murton
doaj  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

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