Results 101 to 110 of about 18,260,517 (415)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Influence of deprivation on health care use, health care costs, and mortality in COPD

open access: yesInternational Journal of COPD, 2018
Peter F Collins,1–3 Rebecca J Stratton,1 Ramesh J Kurukulaaratchy,4,5 Marinos Elia1 1NIHR Nutrition Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton General Hospital, University Hospital Southampton NHS ...
Collins PF   +3 more
doaj  

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Health Care Fraud [PDF]

open access: yes, 2009
Provides an overview of trends in fraud and abuse involving private insurance, Medicaid, and Medicare; types of schemes; risk factors; and consequences.
Nancy Lopez   +2 more
core  

Rationing health care [PDF]

open access: yesBMJ, 1996
What is the role of the National Institute for Health and Clinical Excellence (NICE) in the rationing process and how can the issue of rationing be better managed?
openaire   +5 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Improving Health Care [PDF]

open access: yes, 1972
This essay confirms Dr. Bornemeier\u27s personal concern as well as organized medicine\u27s concern for the medically deprived. At the same time it realistically appraises the progress which the profession has made to meet the medical-social challenges ...
Bornemeier, Walter C.
core   +1 more source

Health care-associated infections – an overview

open access: yesInfection and Drug Resistance, 2018
Health care-associated infections (HCAIs) are infections that occur while receiving health care, developed in a hospital or other health care facility that first appear 48 hours or more after hospital admission, or within 30 days after having received ...
Mainul Haque   +3 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

A governance model for the application of AI in health care

open access: yesJ. Am. Medical Informatics Assoc., 2019
As the efficacy of artificial intelligence (AI) in improving aspects of healthcare delivery is increasingly becoming evident, it becomes likely that AI will be incorporated in routine clinical care in the near future.
S. Reddy   +3 more
semanticscholar   +1 more source

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