Results 131 to 140 of about 18,260,517 (415)

Adolescent Sexual and Reproductive Health:Report on an Assessment and Review of Training Materials [PDF]

open access: yes
Young people in Tanzania face a range of serious reproductive health risks – from early unwanted pregnancy and unsafe abortion to sexually transmitted infections, including HIV/AIDS.
Family Care International , (FCI)   +1 more
core  

High and Rising Health Care Costs: Demystifying U.S. Health Care Spending [PDF]

open access: yes, 2008
Reviews the data used to measure U.S. healthcare costs and examines long- and short-term trends, whether costs are too high, how they compare to those of other developed nations, and what factors are driving the growth.
Paul B. Ginsburg
core  

Integrating child eye health within primary health care: a case study

open access: yesCommunity Eye Health Journal, 2018
Few children have access to specialised eye care in Tanzania. However, ten simple activities have been shown to reduce the risk of childhood blindness and eye disease dramatically.
Milka Mafwiri   +2 more
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Strengthening primary care in Singapore: aligning vital health system components

open access: yesPolicy Design and Practice
Primary health care in Singapore faces significant challenges related to fragmentation and misaligned incentives, despite the country’s impressive health outcomes and efficient healthcare system.
M. Ramesh, Jiwei Qian
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Baylor Health Care System: High-Performance Integrated Health Care [PDF]

open access: yes, 2009
Describes the organization's implementation of a quality infrastructure and its strategies, interventions to improve clinical preventive services, training, and adoption of electronic health records and other quality innovations.
Len M. Nichols, Tom Emswiler
core  

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