Results 91 to 100 of about 1,354,273 (314)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Creating tomorrow in health care : a special report by the Governor's Task Force on Health Care [1991] [PDF]

, 1991
"November 1991."A special report by the Governor's Task Force on Health Care -- Dear Fellow Kansan -- Governor's Task Force On Health Care -- Task Force Members -- Acknowledgments -- Creating Tomorrow In Health Care -- Introduction -- The Problem: Cost ...
Kansas Governor's Task Force on Health Care
core   +2 more sources

Informing the development of services supporting self-care for long term mental health conditions: A mixed method study of community based mental health initiatives in England [PDF]

, 2012
Background Supporting self-care is being explored across health care systems internationally as an approach to improving care for long term conditions in the context of ageing populations and economic constraint.
Simons, L., Lucy Simons, Self Care in Mental Health research team, Gillard, S., Turner, K., Adams, Katie, Miller, Stephen, Team, Self Care Mental Hlth Res, White Sarah, Edwards Christine, Lucock Mike, Turner, K, Rachel White, Gillard Steve, Lucock, M., White, R., Edwards, C, Turner Kati, Edwards, C., Simons Lucy, Adams, K., White, Sarah, Gillard, S, Simons, L, Miller, S., Adams, K, Lucock, Mike, White Rachel, Kati Turner, Gillard, Steve, Edwards, Christine, White, Rachel, Turner, Kati, Stephen Miller, Lucock, M, Simons, Lucy, null null, Christine Edwards, Mike Lucock, Miller, S, Sarah White, Adams Katie, White, S., White, R, White, S, Miller Stephen, Steve Gillard, Katie Adams   +47 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

State Medicaid coverage of family planning services / [PDF]

, 1995
"December 1995.""Prepared by the National Governors' Association under a contract (No. 500-92-0045) with the Health Care Financing Administration ...
Orloff, Tracey M., United States. Health Care Financing Administration., National Governors' Association., Andrews, Chryl Y.   +3 more
core  

Analysis of processes and costs of alternative packaging options of sterile goods in hospitals – a case study in two German hospitals

Health Economics Review, 2019
Background Hospitals should monitor the costs of all direct and indirect processes in order to achieve efficiency and safeguard financial sustainability. One neglected process with significant costs is the processing of reusable medical devices and their
Markus Krohn, Josefine Fengler, Thomas Mickley, Steffen Flessa   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The patient as the pivot point for quality in health care delivery [PDF]

, 1995
Click on the link below to access the article (may not be free).Health care enterprises make comprehensive and durable changes in people. This human-centered purpose defines the fundamental nature of quality in health care settings.
Lengnick-Hall, Cynthia A.
core  

Collaboratively planning for medicines administration: a survey evaluation [PDF]

, 2011
Aims This survey evaluated the experiences of mental health nurses who had undergone assessment of their competence in the administration of medicines using established assessment frameworks.
Smith, George, Rebecca, Burgess-Dawson, Dewhirst, Kate, GEORGE SMITH, Hemingway, Steve, REBECCA BURGESS-DAWSON, Baxter, Hazel, Burgess-Dawson, Rebecca, STEVE HEMINGWAY, HAZEL BAXTER, KATE DEWHIRST   +10 more
core   +1 more source

Evidence mapping for decision making: feasibility versus accuracy – when to abandon high sensitivity in electronic searches

GMS German Medical Science, 2016
Background: Mapping the evidence is a relatively new methodological approach and may be helpful for the development of research questions and decisions about their relevance and priority.
Buchberger, Barbara, Krabbe, Laura, Lux, Beate, Mattivi, Jessica Tajana   +3 more
doaj   +1 more source