Results 61 to 70 of about 3,096,902 (313)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

New Ideas to Help the Aquino Administration Achieve its Health Agenda [PDF]

open access: yes
One of the inaugural commitments made by the Philippines` new administration is the provision of quality and affordable health care for each and every Filipino. To achieve this, a strategic health agenda is needed. This Policy Note offers a few new ideas
Lavado, Rouselle F.
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Administrative Challenges to the Integration of Oral Health With Primary Care [PDF]

open access: yes, 2016
Inadequate access to preventive oral health services contributes to oral health disparities and is a major public health concern in the United States.
Gano, Laura   +4 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Understanding EMS response times: a machine learning-based analysis

open access: yesBMC Medical Informatics and Decision Making
Background Emergency Medical Services (EMS) response times are critical for optimizing patient outcomes, particularly in time-sensitive emergencies. This study explores the multifaceted determinants of EMS response times, leveraging machine learning (ML)
Peter Hill   +4 more
doaj   +1 more source

Coexisting Values in Healthcare and the Leadership Practices That Were Found to Inspire Followership Among Healthcare Practitioners [PDF]

open access: yes, 2019
Healthcare delivery in the United States has a storied history that has led the American public to expect that their Health Care Practitioners (HCPs) will personally and professionally enact values such as altruism, benevolence, equality, and capability.
Stewart, Christopher W.
core   +1 more source

Executive Authority to Reform Health: Options and Limitations [PDF]

open access: yes, 2009
Presidential power has provoked increasingly vigorous debate since the turn of this century. In recent years, scholars and lawyers have been grappling with how Congress\u27s dictates may limit the President\u27s Commander-in-Chief power to detain enemy ...
Chugh, Madhu
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Costing of helicopter emergency services- a strategic simulation based on the example of a German rural region

open access: yesHealth Economics Review, 2020
Background Helicopter emergency services (HEMS) are of increasing relevance for emergency medical services (EMS) of developed countries. Despite the known cost intensity of HEMS, there is only very limited knowledge of its cost dynamics and structures ...
Johann Röper   +3 more
doaj   +1 more source

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