Results 91 to 100 of about 4,397,138 (309)

Examining the impact of accreditation on a primary healthcare organization in Qatar

BMC Medical Education, 2018
Background Although a modest body of literature exists on accreditation, little research was conducted on the impact of accreditation on primary healthcare organizations in the Middle East.
Alia Ghareeb, Hana Said, Mohamad El Zoghbi   +2 more
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Demographic and socioeconomic determinants of adherence in digital patient-reported outcomes among patients with chronic diseases

npj Digital Medicine
Engaging patients in the digital collection of electronic patient-reported outcome measures (ePROMs) and experience measures (ePREMs) is desirable for equitable, patient-centred chronic disease management; however, adherence remain unclear.
Janis Nikkhah, Alessandro Campione, Viktoria Steinbeck, Laura Wittich, Christoph Pross, Reinhard Busse   +5 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Dimensions of Health Care Management Professionalization: A Scoping Review. [PDF]

Med J Islam Repub Iran, 2023
Mahmoudian P, Jafari M, De Roodenbeke E, Maleki M.   +3 more
europepmc   +1 more source

Research On Awareness Of Hospital Managers About Chronic Diseases And The Care By Multidisciplinary Teams Towards Sustainable Health Care Services In Vietnam [PDF]

, 2012
This study focused on top management in health care services in Vietnam. Kajian ini tertumpu kepada perkhidmatan penjagaan kesihatan yang diberikan oleh pengawai atasan di ...
Hayashi, Yumiko
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The Community Health Fund:Assessing Implementation of New Management procedures in Hanang District,Tanzania [PDF]

, 2004
A key obstacle to the success of community-based health insurance initiatives in Africa is the dearth of well-trained health managers who can design and run the insurance schemes in a viable manner.
Musau, Stephen
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source